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Radiographic features of COVID-19 based on an initial cohort of 96 patients in Singapore
Authors:Hau Wei Khoo  Terrence Chi Hong Hui  Salahudeen Mohamed Haja Mohideen  Yeong Shyan Lee  Charlene Jin Yee Liew  Shawn Shi Xian Kok  Barnaby Edward Young  Sean Wei Xiang Ong  Shirin Kalimuddin  Seow Yen Tan  Jiashen Loh  Lai Peng Chan  Angeline Choo Choo Poh  Steven Bak Siew Wong  Yee-Sin Leo  David Chien Lye  Gregory Jon Leng Kaw  Cher Heng Tan
Abstract:INTRODUCTIONChest radiographs (CXRs) are widely used for the screening and management of COVID-19. This article describes the radiographic features of COVID-19 based on an initial national cohort of patients.METHODSThis is a retrospective review of swab-positive patients with COVID-19 who were admitted to four different hospitals in Singapore between 22 January and 9 March 2020. Initial and follow-up CXRs were reviewed by three experienced radiologists to identify the predominant pattern and distribution of lung parenchymal abnormalities.RESULTSIn total, 347 CXRs of 96 patients were reviewed. Initial CXRs were abnormal in 41 (42.7%) out of 96 patients. The mean time from onset of symptoms to CXR abnormality was 5.3 ± 4.7 days. The predominant pattern of lung abnormality was ground-glass opacity on initial CXRs (51.2%) and consolidation on follow-up CXRs (51.0%). Multifocal bilateral abnormalities in mixed central and peripheral distribution were observed in 63.4% and 59.2% of abnormal initial and follow-up CXRs, respectively. The lower zones were involved in 90.2% of initial CXRs and 93.9% of follow-up CXRs.CONCLUSIONIn a cohort of swab-positive patients, including those identified from contact tracing, we found a lower incidence of CXR abnormalities than was previously reported. The most common pattern was ground-glass opacity or consolidation, but mixed central and peripheral involvement was more common than peripheral involvement alone.
Keywords:chest radiographs   coronavirus disease 2019   SARS-CoV-2
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