Early infection in post-autologous hematopoietic stem cell transplant patients: Princess Noorah Oncology Center experience |
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| Authors: | Roaa S Gassas Ahmed N Absi Abdulrahman A Alghamdi Ahmed S Alsaeed Sameer M Alamoudi Ihab Y Hemaidi Majed D Alahmadi Walaa A Rajkhan Mannar M Khalil Saleem K Dadah Ahmed S Higazi Amani S Ahmed |
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| Institution: | From the Department of Adult Hematology Blood and Marrow Transplant (Gassas), King Abdulaziz Medical City, National Guard Health Affairs; and from the Adult Hematology Blood and Marrow Transplant Unit (Absi, Alghamdi, Alsaeed, Alamoudi, Hemaidi, Alahmadi, Rajkhan, Khalil, Dadah, Higazi, Ahmed), Princess Noorah Oncology Center, Jeddah, Kingdom of Saudi Arabia. |
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| Abstract: | Objectives:To assess local epidemiology and risk factors for bacterial, fungal, and viral infections among the autologous bone marrow transplant population.Methods:This study is a retrospective correlational cohort design comprising 150 adult patients who underwent autologous transplants at Princess Noorah Oncology Center, Jeddah, Saudi Arabia between 2014 and 2020.Results:The study findings indicate that bacterial infection prevalence differed significantly across the different disease status pre-salvage as patients with the relapsed disease were more likely to have bacterial infections. The median of engraftment days differed significantly between those who had a bacterial infection and those who did not. Interestingly, previous pneumonia infection had a positive relationship with the number of hospital stays.Conclusions:Bacterial infections are the dominant type of infection among the autologous patient population. The research reflects authentic practice and reports unique characteristics of autologous transplant patients in terms of the prevalence and types of infection these patients experience. |
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| Keywords: | bone marrow transplantation lymphoma infection relapsed myeloma |
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