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青年肝静脉型布加综合征患者血浆同型半胱氨酸与维生素B12及叶酸浓度的相关性研究
引用本文:田浩,徐浩,祖茂衡.青年肝静脉型布加综合征患者血浆同型半胱氨酸与维生素B12及叶酸浓度的相关性研究[J].检验医学与临床,2011,8(24):2949-2950,2953.
作者姓名:田浩  徐浩  祖茂衡
作者单位:1. 江苏省新沂市人民医院肿瘤科,221400
2. 徐州医学院附属医院介入科,江苏徐州,221402
基金项目:国家十一五科技计划支撑课题(2006038073024)
摘    要:目的研究青年肝静脉型布加综合征(BCS)患者血浆维生素B12、叶酸与同型半胱氨酸(Hcy)的相关性。方法青年肝静脉型BCS患者60例,同期健康对照组60例,均留取空腹肘静脉血,BCS患者介入治疗时另取肝静脉血,免疫荧光反应测定血浆Hcy浓度,放射免疫法测定血清维生素B12及叶酸浓度。结果 BCS组肝静脉及肘静脉血Hcy分别为(21.40±9.82)和(20.38±8.40)mmol/L]浓度均高于健康对照组(16.64±5.16)mmol/L],两组间差异有统计学意义(P<0.05)。BCS组血清叶酸及维生素B12浓度分别为(4.10±1.85)mg/L和(432.48±104.36)ng/L,健康对照组分别为(6.40±1.91)mg/L和(447.60±115.48)ng/L,两组差异无统计学意义。结论青年肝静脉型BCS患者体内存在高Hcy浓度状态,高Hcy浓度状态与体内叶酸、维生素B12浓度无明显相关性。

关 键 词:布加综合征  同型半胱氨酸血症  叶酸  维生素B12

Study on the relativity of the plasma Hcy,Vit B_(12) and serum folic acid levels in young patients of BCS with hepatic vein obstruction
TIAN Hao,XU Hao,ZU Mao-heng.Study on the relativity of the plasma Hcy,Vit B_(12) and serum folic acid levels in young patients of BCS with hepatic vein obstruction[J].Laboratory Medicine and Clinic,2011,8(24):2949-2950,2953.
Authors:TIAN Hao  XU Hao  ZU Mao-heng
Institution:TIAN Hao1,XU Hao2,ZU Mao-heng2
Abstract:Objective To study the relativity of the plasma homocysteine(Hcy),serum folic acid and Vit B12 levels in young patients of Budd-Chiari syndrome(BCS) with hepatic vein obstructive.Methods 60 young patients of BCS with hepatic vein obstructive and 60 healthy people with the same conditions were collected and taking the fasting vein blood,and the BCS patients were taking hepatic venous blood.The serum folic acid,Vit B12 were tested by radioimmunoassay,and plasma Hcy was measured by immunofluorescence.Results T...
Keywords:Budd-Chiari syndrome  homocysteine  folic acid  Vit B12  
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