Time course of ventilatory drive in patients with kyphoscoliosis before and during intermittent ventilation |
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Authors: | Feldmeyer F Randerath W Rühle K H |
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Affiliation: | Abteilung für Pneumologie, Allergologie und Schlafmedizin, Klinik Ambrock, Hagen. |
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Abstract: | The aim of this retrospective study was to investigate the mouth-occlusion-pressure under CO2-stimulation in five patients (3 women, 2 men) suffering from kyphoscoliosis of different aetiology whilst being under noninvasive ventilation for respiratory muscle fatigue. Ten months after initiation of noninvasive ventilation we could demonstrate a marginal improvement of respiratory muscle strength but the P0.1 CO2-decreased slightly. We conclude that this decrease might be due to an increase in tidal volume allowing for a reduction in respiratory rate. |
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