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占替诺烟酸盐治疗脑梗死146例
引用本文:王世伟,任耀先,李淑忠,申德鑫,周文志,王志力.占替诺烟酸盐治疗脑梗死146例[J].中国新药与临床杂志,1993(1).
作者姓名:王世伟  任耀先  李淑忠  申德鑫  周文志  王志力
作者单位:锦州市中心医院内科,锦州市中心医院内科,锦州市中心医院内科,锦州市中心医院内科,锦州市黑龙制药厂,锦州市黑龙制药厂 锦州 121004,锦州 121004,锦州 121004,锦州 121004,锦州 121000,锦州 121000
摘    要:占替诺烟酸盐治疗脑梗死146例(男120例,女26例,年龄63±7a),剂量200mg tid, po, 30d为一个疗程。并与相同条件的112例患者用右旋糖酐-40每日静滴500mL,持续4wk作对照。占替诺烟酸盐的总有效率89.7%,对照组为68.7%,P<0.05。无副作用,可长期服用。

关 键 词:脑梗死/药物疗法  占替诺烟酸盐/治疗应用  右旋糖酐类/治疗应用  茶碱

Therapy of cerebral infarction with xantinol nicotinate in 146 patients
WANG Shi-Wei,REN Yao-Xian,LI Shu-Zhong,SHEN De-Xin.Therapy of cerebral infarction with xantinol nicotinate in 146 patients[J].Chinese Journal of New Drugs and Clinical Remedies,1993(1).
Authors:WANG Shi-Wei  REN Yao-Xian  LI Shu-Zhong  SHEN De-Xin
Abstract:One hundred forty-six patients of cerebral infarction (M 120, F 26, age 63 + 7 a) were treated with xantinol nicotinate 200 mg tid, po, for 30 d. The other 112 similar patients were treated with dextran-40 500 mL iv gtt, qd, for 4 wk as controls. Result showed that the total response rate in the former group (89. 7%) was better than that in the control group (68. 7%) (P<0. 05). There were no remarkable adverse effects. It is suggested that this remedy may be used for a long period.
Keywords:cerebral infarction/drug therapy  xantinol nicotinate/ therapeutic use  dextrans/therapeutic use  theophylline  
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