精索静脉曲张不育症患者精索静脉血气分析

目的 探讨精索静脉曲张（varicocele,VC）导致男性不育的具体发病机制.方法 选择50例VC不育症患者及40例对照组作为研究对象,分别取其左侧精索内静脉以及周围静脉血进行血气分析,然后比较.结果 （1）VC不育症患者左侧精索静脉血中的PH、PO2、SO2及HCO3-低于外周静脉血（P＜0.05）,PCO2及K＋高于外周静脉血（P＜0.05）,而其他指标差异无统计学意义（P＞0.05）.（2）VC不育症患者左侧精索静脉血中的PH、PO2、SO2及HCO3-低于对照组（P＜0.05）,40例对照组PCO2及K＋高于对照组（P＜0.05）,而其他指标差异无统计学意义（P＞0.05）.（3）VC不育症患者精液密度及活率低于对照组（P＜0.05）,畸形率高于对照组（P＜0.05）.结论 VC不育症患者精索静脉中的PH、PO2、SO2、HCO3-降低和PCO2、K＋升高是导致精液密度及活率降低同时畸形率升高进而引起男性不育的原因.

Analysis of the spermatic vein blood gas from the infertility patients with varicocele

Objectives To investigate the nosogenesis of why varicocele can result in infertility. Methods The left spermatic and peripheral vein blood was taken from 50 infertility patients with varicocele and 40 normal cases,and the blood gas was mearsured. Results （ 1 ） The PH, PO2, SaO2, HCO3 - of the left spermatie vein blood was lower than that of the peripheral vein blood from the male with varicocele （ P 〈 0.05 ）, the PCO2, K of the left spermatic vein blood was higher than that of the peripheral vein blood from the male with varicocele（ P 〈0. 05 ）, but the other indexof them was not significant（ P 〉 0.05 ）. （2） The PH, PO2 , SaO2 , HCO3 - of the left spermat- ic vein blood from the male with varicocele was lower than that from the normal male（ P 〈 0.05 ）, the PCO2, K of the left spermatic vein blood from the male with varicocele was higher than that from the normal male（ P 〈 0.05 ）, but the other index of them was not significant （ P 〉 0.05 ）. （3） The density and motility rate of sperm fromthe male with 4 varicocele was lower than that from the normal male（ P 〈 0.05 ）, and the abnormal rateof sperm from the male with varicocele was higher than that from the normal male （ P 〈 0.05 ）. Conclusions The depression of the PH , PO2, SaO2, HCO3 - and the rise of the PC02, K in the spermatic vein blood from the infertility patients with the varicocele may be the cause of the depression of the density and motility rate of sperm and the rise oftheabnormal ra teof sperm which can result in infertility.