Variation in the Amount of Hemoglobin S in a Patient with Sickle Cell Trait and Megaloblastic Anemia |
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Authors: | HELLER, PAUL YAKULIS, VINCENT J. EPSTEIN, ROBERT B. FRIEDLAND, SIGMUND |
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Affiliation: | 1 Research Laboratory and the Medical Service, Veterans Administration WestSide Hospital, and the Department of Medicine, University of Illinois College of Medicine,Chicago, Ill.
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Abstract: | A patient with sickle cell trait and nutritional megaloblastic anemia wasfound to have a much smaller proportion of hemoglobin S during the megaloblastic phase than after recovery. This observation suggests preferential synthesis of hemoglobin A by megaloblastic bone marrow in the presence of theA-S trait. Submitted on July 30, 1962 Accepted on November 9, 1962 |
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