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Variation in the Amount of Hemoglobin S in a Patient with Sickle Cell Trait and Megaloblastic Anemia
Authors:HELLER, PAUL   YAKULIS, VINCENT J.   EPSTEIN, ROBERT B.   FRIEDLAND, SIGMUND
Affiliation:1 Research Laboratory and the Medical Service, Veterans Administration WestSide Hospital, and the Department of Medicine, University of Illinois College of Medicine,Chicago, Ill.
Abstract:A patient with sickle cell trait and nutritional megaloblastic anemia wasfound to have a much smaller proportion of hemoglobin S during the megaloblastic phase than after recovery. This observation suggests preferential synthesis of hemoglobin A by megaloblastic bone marrow in the presence of theA-S trait.

Submitted on July 30, 1962 Accepted on November 9, 1962
Keywords:
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