| 内皮祖细胞与动脉粥样硬化蚀损斑块合并血栓形成 |
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| 引用本文： | 陈玉国,徐峰,张运.内皮祖细胞与动脉粥样硬化蚀损斑块合并血栓形成[J].心血管病学进展,2006,27(1):31-33. |
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| 作者姓名： | 陈玉国 徐峰 张运 |
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| 作者单位： | 1. 山东大学齐鲁医院急诊科,山东,济南,250012
2. 山东大学齐鲁医院心内科,山东,济南,250012 |
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| 摘 要： | 动脉粥样硬化易损斑块是急性冠脉综合征和心脏缺血性猝死的重要病理基础。蚀损斑块是易损斑块的重要病理类型之一,其主要特点:斑块表面大面积内皮细胞脱落和血栓形成。目前有关蚀损斑块合并血栓形成机制的研究罕见。近年的研究认为,内皮祖细胞参与血管内皮损伤后的修复。因此,内皮祖细胞可能参与蚀损斑块合并血栓形成,或对其有治疗作用,此方面研究国内外未见,值得探讨。
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| 关 键 词： | 动脉粥样硬化 蚀损斑块 血栓形成 内皮祖细胞 |
| 文章编号： | 1004-3934(2006)01-0031-03 |
| 收稿时间： | 2005-07-10 |
| 修稿时间： | 2005年7月10日 |
Relationship Between Endothelial Progenitor Cells and Atherosclerotic Plaque Erosion and Thrombosis |
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| CHEN Yu-guo,XU Feng,ZHANG Yun.Relationship Between Endothelial Progenitor Cells and Atherosclerotic Plaque Erosion and Thrombosis[J].Advances in Cardiovascular Diseases,2006,27(1):31-33. |
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| Authors: | CHEN Yu-guo XU Feng ZHANG Yun |
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| Institution: | 1. Department of Emergency, Qilu Hospital of Shandong University, Jinan 250012, China; 2. Department of Cardiology, Qilu Hospital of Shandong University, Jinan 250012, China |
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| Abstract: | Atherosclerotic vulnerable plaque is considered as an important pathologic basis of acute coronary syndrome and sudden cardiac ischemic death.Eroded plaque,which is characterized with endothelial denudation and thrombosis,is a type of vulnerable plaque.The mechanisms of eroded plaque are poorly understood.Recent researches demonstrated that endothelial progenitor cells play an important role in repair of injured endothelium.So the relationship between endothelial progenitor cells and eroded plaque and thrombosis is worth investigating. |
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| Keywords: | atherosclerosis eroded plaque/plaque erosion thrombosis endothelial progenitor cell |
| 本文献已被 CNKI 维普 万方数据 等数据库收录！ |
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