| 奥斯曼生眉液超滤工艺的研究 |
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| 引用本文： | 刘庆华,于萍,严欢,张沾.奥斯曼生眉液超滤工艺的研究[J].海峡药学,2014,0(4):22-25. |
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| 作者姓名： | 刘庆华 于萍 严欢 张沾 |
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| 作者单位： | 刘庆华 (新疆奥斯曼生物资源有限公司 乌鲁木齐830026 新疆维吾尔自治区药物研究所乌鲁木齐830007)； 于萍(新疆奥斯曼生物资源有限公司 乌鲁木齐830026)； 严欢 (新疆维吾尔自治区药物研究所乌鲁木齐830007)； 张沾(新疆奥斯曼生物资源有限公司 乌鲁木齐830026)； |
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| 基金项目： | 新疆维吾尔自治区经信委特色轻工项目 |
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| 摘 要： | 目的：研究奥斯曼生眉液的超滤工艺。方法采用截留相对分子量分别为6000和30000的聚丙烯中空纤维膜，以超滤前后药液中吲哚苷和鞣质含量为指标，采用单因素考察和正交实验方法优选超滤的最佳工艺参数。结果截留相对分子质量为30000的超滤膜有较好的分离提纯效果，最佳工艺参数为：料液加水稀释5倍，调pH至6.0，常温、操作压力0.10Mpa的条件下膜分离3遍。结论超滤工艺能有效提高产品有效物的含量和解决产品稳定性问题。
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| 关 键 词： | 超滤 奥斯曼生眉液 吲哚苷 鞣质 单因素 正交 |
Research of Ultrafiltration Techniques on Water-extraction of Osmen Plant Eyebrow Growing liquid |
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| LIU Qing-hua,YU Ping,YAN Huan,ZHANG Zhan.Research of Ultrafiltration Techniques on Water-extraction of Osmen Plant Eyebrow Growing liquid[J].Strait Pharmaceutical Journal,2014,0(4):22-25. |
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| Authors: | LIU Qing-hua YU Ping YAN Huan ZHANG Zhan |
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| Institution: | 1. Xinjiang Osmen Biological resources Co. , Ltd. Urumqi 830026, China;2 Xinjiang Institute of Marteria Medica, Urumqi 800007, China) |
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| Abstract: | OBJECTIVE To explore the optimize the ultrafiltration technology of Osmen Plant Eyebrow Growing 1iquid.METHODS The polypropylene （ PP） membrane of different aperture 6000 and 30000 were studied on the applicability with water-extraction of Osmen.The propermolecular weight retention was optimized with removal of liq-uid impurities andindole glycosides as index ,while the proper ultrafiltration condition was optimized by single factor and orthogonal tests.RESULTS The PP membrane with 30000 interceptionmolecular weight had better separation efficiency and the preferred operation parameters were 0.10 Mpa of pressure ,the pH adjusted to 6.0 ,at room temper-atureand separation 3 times of water-extraction.CONCLUSION Ultrafiltration process can effectively improve the effective substance content of products and solve the problem of product stability. |
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| Keywords: | Ultrafiltration Osmen Plant Eyebrow Growing 1iquid Single factor Orthogonal tests |
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