| The Relationship between Drug-and Chemical-exposure and Birth Defects during Pregnancy |
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| 引用本文： | 沈启芳 张忠恕 方可娟 丁亦诺 顾江 王仁礼 杨跃英 李海放 蒋秀蓉 薛寿征. The Relationship between Drug-and Chemical-exposure and Birth Defects during Pregnancy[J]. 生殖与避孕(英文版), 1994, 5(1): 230-240 |
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| 作者姓名： | 沈启芳 张忠恕 方可娟 丁亦诺 顾江 王仁礼 杨跃英 李海放 蒋秀蓉 薛寿征 |
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| 作者单位： | ShanghaiInsrituteofPlannedParenthoodResearch,Shanghai,200032,China |
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| 摘 要： | A case-control study was conductedin 36 hospitals of the urban and suburban areas of Shanghai about the relationships between birth defects and drug use and chemieal exposures during pregnancy in the period of July 1987-December 1990. The case group was composed of 1.609 subjects, and the control group 3,218 cases. On statistical analysis, it was found that a correlation existed between birth defects and the intake of APC and diazepam, and the exposure to pesticides, organic soh, ents, benzene, synthetic resin and physical factors (noises) on the part of the mother, and the exposure to harmful chemicals and physical factors and the smoking of 20 or more cigarettes a day on the part of the father. It is also found that the familial hereditary history of the parents and muhigravidio,, malnutrition, common colds, hepatitis and diarrhea during pregnancy may also be related to the birth defects.
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| 关 键 词： | 麻醉药 化学暴露 英国 怀孕 营养不良 |
The Relationship between Drug-and Chemical-exposure and Birth Defects during Pregnancy |
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| Shen Qi-fang,Zhang Zhong-shu,Fang Ke-juan,Ding Yi-non,Gu Jiang,Wang Ren-li,Yang Yao-ying,Li Hai-fang,Jiang Xui-rong,and Xue Shou-zheng. The Relationship between Drug-and Chemical-exposure and Birth Defects during Pregnancy[J]. Journal of Reproduction and Contraception, 1994, 5(1): 230-240 |
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| Authors: | Shen Qi-fang Zhang Zhong-shu Fang Ke-juan Ding Yi-non Gu Jiang Wang Ren-li Yang Yao-ying Li Hai-fang Jiang Xui-rong and Xue Shou-zheng |
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| Abstract: | A case-control study was conducted in 36 hospitals of the urban and suburban areas of shanghai about the relationships between birth defects and drug use and chemical exposures during pregnancy in the period of july 1987-December 1990.The case group was composed if 1,609 subjects,and the control group 3,218 cases.On stall'stical analysl's,it was.found that a correlation ed'sted between birth defects and the intake Of APC and diazepam,and the exposure to pesticides,organic solvents.benzene,synthetic resin and physical.factors(noises)on foe part of foe mother.and the exposure to harmful chemicals and physical factors and the smoking of 20 or more cigarettes a day on the part Of the father.It is also found that foe familial heredilary history of the parents and multigravavidity,malnutrition,common colds,hepatitis and diarrhea during pregnancy may also be relaied to the birth defects. |
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| Keywords: | Birth defects Drug Chemical Pregnancy |
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