46例感染中毒症临床资料分析

目的分析46例感染中毒症患者血培养致病菌的种类、耐药谱、临床特征及预后。方法对我院住院诊断为感染中毒症的46例患者血培养和药敏结果及临床资料进行回顾性分析。结果46例感染中毒症患者血培养共分离出致病菌49株革兰阳性菌24株(49.0%),革兰阴性菌20株(40.8%),真菌5株(10.2%)。多种菌株对常用抗生素出现多重耐药。46例患者治愈33例(71.7%),死亡5例(10.9%),自动出院8例。结论随着新型抗生素在临床的广泛应用,革兰阳性菌感染中毒症有上升的趋势,并且呈多重耐药。

Clinical Analysis of 46 Cases With Septicemia

Objective:To study the bacteria strain and resistance to commonly used antibiotics, clinical characteristics and prognosis of 46 patients with septicemia.Methods:The results of blood cultures and drug sensitive test of 46 patients diagnosed as septicemia in our hospital were analysed retrospectively. Results: Fourty-nine strains of microorganisms were isolated from blood cultures of 46 septic patients including 24 strains( 49.0% ) of gram positive bacteria, 20 strains ( 40.8% ) of gram negative bacteria and 5 strains( 10.2% ) of fungus. Many strains developed multi-drug resistance to the commonly used antibiotics. Thirty-three ( 71.7% ) of 46 cases were cured, 5( 10.9% ) cases died and the other 8 cases gave up treatment at own risk.Conclusion:With the clinical extensive use of new generation antibiotics,gram positive bacteria septicemia is increasing, and shows a trend of on multi-drug resistance.