宫颈癌后装治疗用甘氨双唑钠增敏40例

目的：探讨宫颈癌患者后装治疗用甘氨双唑钠放射治疗的增敏作用。方法：85例接受放射治疗的宫颈癌患者，随机分为增敏组40例和常规组45例，常规组常规放疗，增敏组放疗方案同常规组，但后装治疗时用甘氨双唑钠增敏。结果：增敏组肿瘤完全消退38例（95％），肿瘤消退平均后装次数2．9次，优于常规组肿瘤完全消退35例（85％），肿瘤消退平均后装次数4．5次（P〈0．05），肿瘤消退时间约提前1．6周。两组急性放射性肠炎、骨髓抑制发生率无统计学差异。结论：后装治疗前使用甘氨双唑钠可达放射增敏目的。

The effect of CMNa for cervical carcinoma patients treated by brachytherapy

Objective：To explore the effect of radiosensitizer（CMNa） for cervical carcinoma patients. Metheds： All 85 patients were enrolled into two groups ： control group 45 cases received radiotherapy alone; radiosensitize group 40 cases received radiotherapy add radiosensitizer （CMNa） （ only braehy - therapy add CMNa）. Results： CR in the radiosensitize group was 95% , in the control group was 85%, （P 〈 0.05 ） , the time reaching CR in the radiosensitize group was shorter;virulent radiation enterocolitis and blood toxicity in two groups were resembled. Conclusion：CMNa can increase cervical tumor radiosensitivity in brachytherapy.