| 栀子中2个成分的分离鉴定及不同采收期栀子样品的比较分析 |
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| 引用本文： | 于晓蕾,李艳芳,苏瑞强,赵志全.栀子中2个成分的分离鉴定及不同采收期栀子样品的比较分析[J].中国实验方剂学杂志,2015,21(2):40-43. |
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| 作者姓名： | 于晓蕾 李艳芳 苏瑞强 赵志全 |
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| 作者单位： | 鲁南制药集团股份有限公司,中药制药共性技术国家重点实验室,山东省中药制药新技术重点实验室,山东临沂 276006 |
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| 基金项目： | 国家重点基础研究发展计划(973计划)项目(2012CB724001) |
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| 摘 要： | 目的:分离制备栀子药材中化学成分,建立栀子中该成分HPLC含量测定法。方法:色谱条件采用Kromasil C18色谱柱(4.6 mm×250 mm,5μm),以乙腈-0.1%磷酸水溶液(18∶82)为流动相,流速1.0 m L·min-1,检测波长327 nm,柱温40℃。结果:从栀子药材中分离鉴定出6″-对香豆酰京尼平龙胆双糖苷(1),3,5-二-O-咖啡酰基-4-O-(3-羟基-3-甲基)戊二酰基奎宁酸(2)2个成分;这2个成分在0.118 8~1.188,0.122 8~1.228μg线性关系良好;平均回收率分别为99.23%,100.4%,RSD分别为2.4%,2.3%;栀子不同采收期对2种成分含量影响较大。结论:本试验结果能较好地反映栀子不同采收期成分的变化,可为栀子药材质量标准的完善提供参考。
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| 关 键 词： | 栀子 6"-对香豆酰京尼平龙胆双糖苷 3 5-二-O-咖啡酰基-4-O-(3-羟基-3-甲基)戊二酰基奎宁酸 |
| 收稿时间： | 2014/3/31 0:00:00 |
Isolation, Identification of Two Consitituents in Gardeniae Fructus and Their Quantitative Analysis in Different Harvesting Time |
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| YU Xiao-lei,LI Yan-fang,SU Rui-qiang and ZHAO Zhi-quan.Isolation, Identification of Two Consitituents in Gardeniae Fructus and Their Quantitative Analysis in Different Harvesting Time[J].China Journal of Experimental Traditional Medical Formulae,2015,21(2):40-43. |
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| Authors: | YU Xiao-lei LI Yan-fang SU Rui-qiang and ZHAO Zhi-quan |
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| Institution: | Lunan Pharmaceutical Group Co. Ltd., State Key Laboratory of Generic Manufacture Technology of Traditional Chinese Medicine(TCM), Shandong Provincial Key Laboratory of New Manufacture Technology of TCM, Linyi 276006, China;Lunan Pharmaceutical Group Co. Ltd., State Key Laboratory of Generic Manufacture Technology of Traditional Chinese Medicine(TCM), Shandong Provincial Key Laboratory of New Manufacture Technology of TCM, Linyi 276006, China;Lunan Pharmaceutical Group Co. Ltd., State Key Laboratory of Generic Manufacture Technology of Traditional Chinese Medicine(TCM), Shandong Provincial Key Laboratory of New Manufacture Technology of TCM, Linyi 276006, China;Lunan Pharmaceutical Group Co. Ltd., State Key Laboratory of Generic Manufacture Technology of Traditional Chinese Medicine(TCM), Shandong Provincial Key Laboratory of New Manufacture Technology of TCM, Linyi 276006, China |
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| Abstract: | |
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| Keywords: | Gardeniae Fructus p-coumaroyl genipin gentiobioside" target="_blank">6"-p-coumaroyl genipin gentiobioside 3 5-di-O-caffeoyl-4-O- (3-hydroxy-3-methyl) glutaroyl quinic acid |
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