Endometriosis: Radionuclide migration through the genital tract in infertile women with endometriosis |
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| Authors: | McQueen, D. McKillop, J.H. Gray, H.W. Callaghan, M. Monaghan, C. Bessent, R.G. |
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| Affiliation: | 1Departments of Gynaecology, Western Infirmary of Glasgow Glasgow G11 6NT, UK 2Department of Nuclear Medicine, Royal Infirmary Glasgow G31 2ER, UK 3Departments of Diagnostic Radiology, Western Infirmary of Glasgow Glasgow G11 6NT, UK 4West of Scotland Health Boards, Department of Clinical Physics and Bio-Engineering 11 West Graham Street, Glasgow G4 9LE, UK |
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| Abstract: | The migration of radionuclide through the genital tract wasobserved, comparing 20 patients with endometriosis and infertilitywith a control group of 23 infertile patients who had a normalpelvis. All patients had patent tubes at laparoscopy and chromopertubation,performed in both groups for the investigation of infertilityand to diagnose the presence and extent of endometriosis. Aradionuclide tubal test, using human albumin microspheres labelledwith 99m-technetium (99mTc) was subsequently undertaken to observethe extent of genital tract migration of radionuclide to uterus,Fallopian tube and peritoneal cavity. The results show thatradionuclide migration to the peritoneal cavity was impairedin patients with endometriosis, compared with the control group(30 versus 83%, respectively; P < 0.001). There was no relationshipbetween migration and the severity of endometriosis. We concludethat impaired tubal function may be a cause of infertility insome patients with endometriosis. |
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| Keywords: | endometriosis/radionuclide migration/tubal infertility |
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