| 碱性成纤维细胞因子促进创面修复的临床疗效 |
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| 引用本文： | 李光辉,邹耘,夏仁云. 碱性成纤维细胞因子促进创面修复的临床疗效[J]. 医药导报, 2002, 21(4): 215-217 |
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| 作者姓名： | 李光辉 邹耘 夏仁云 |
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| 作者单位： | 1. 华中科技大学同济医学院附属同济医院骨科,武汉,430030
2. 华中科技大学同济医学院附属同济医院皮肤科,武汉,430030 |
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| 摘 要： | 目的:观察碱性成纤维细胞因子(bFGF)对创面修复的疗效及毒副作用.方法:173例患者分为治疗组89例,其中急性创面55例,慢性难愈合创面34例,采用bFGF局部外用,每平方厘米150活性单位,qd,7 d为1个疗程;对照组84例,其中急性创面50例,慢性难愈合创面34例,除未用bFGF外,其他疗法同治疗组.结果:治疗组较对照组创面修复质量显著提高,创面愈合时间缩短,且无明显毒副作用.结论:bFGF具有促进创面修复作用,有很大临床应用价值.
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| 关 键 词： | 成纤维细胞因子,碱性 创面修复 疗效评价 |
| 文章编号： | 1004-0781(2002)04-0215-03 |
| 修稿时间： | 2001-08-20 |
A Clinical Evaluation of Effectiveness of Basic Fibroblast Growth Factor in Promoting Wound Healing |
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| LI Guang hui ,ZOU Yun ,XIA Ren yun. A Clinical Evaluation of Effectiveness of Basic Fibroblast Growth Factor in Promoting Wound Healing[J]. Herald of Medicine, 2002, 21(4): 215-217 |
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| Authors: | LI Guang hui ZOU Yun XIA Ren yun |
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| Affiliation: | LI Guang hui 1,ZOU Yun 2,XIA Ren yun 1 |
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| Abstract: | Objective:To evaluate the effects of basic fibroblast growth factor (bFGF) on wound healing and the side effects of bFGF. Methods:In this study, 173 patients with various kinds of wounds were recruited and randomly divided into treatment and control groups. The 89 patients (55 with acute wounds and 34 chronic intractable wounds) in the treatment group were treated with local use of bFGF in addition to routine management, while the 84 patients in the control group treated only with routine management. Results:It was found that the time needed for wound healing for those in the treatment group was significantly shorter than that in the control group. Meanwhile, no adverse effect was found in any patients treated with bFGF. Conclusion:bFGF can promote the repairing of wounds. |
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| Keywords: | Basic fibroblast growth factor(bFGF) Wound healing Effectiveness evaluation |
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