| 调节性树突状细胞治疗在器官移植应用 |
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| 引用本文： | 尧凯,施国海,王祥慧. 调节性树突状细胞治疗在器官移植应用[J]. 上海交通大学学报(医学版), 2007, 27(6): 743-746 |
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| 作者姓名： | 尧凯 施国海 王祥慧 |
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| 作者单位： | 上海交通大学,医学院瑞金医院,器官移植中心肾移植科,上海,200025;上海交通大学,医学院瑞金医院,器官移植中心肾移植科,上海,200025;上海交通大学,医学院瑞金医院,器官移植中心肾移植科,上海,200025 |
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| 摘 要： | 树突状细胞(DCs)是一种具有较强可塑性的抗原递呈细胞,可通过不同的方法“程序化”DCs而达到致耐受原特性。近来有资料显示药理学调控DCs可产生强有效的调节性DCs。文章对调节性DCs研究进展及其在器官移植方面的临床应用作一综述。
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| 关 键 词： | 树突状细胞 器官移植 临床应用 |
| 文章编号： | 0258-5898（2007）06-0743-04 |
| 修稿时间： | 2006-09-18 |
Regulatory dendritic cell therapy in organ transplantation |
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| YAO Kai,SHI Guo-hai,WANG Xiang-hui. Regulatory dendritic cell therapy in organ transplantation[J]. Journal of Shanghai Jiaotong University:Medical Science, 2007, 27(6): 743-746 |
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| Authors: | YAO Kai SHI Guo-hai WANG Xiang-hui |
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| Affiliation: | Department of Renal Transplantation, Center of Organ Transplantation, Ruijin Hospital, School of Medicine, Shanghai Jiaotong University, Shanghai 200025, China |
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| Abstract: | Dendritic cells (DCs) are uniquely well-equipped antigen (Ag)-presenting cells. This function of DCs, coupled with their remarkable plasticity, renders them attractive therapeutic targets for immune modulation. Recent data have demonstrated a promising role for pharmacologic treatment as a means of generating potent regulatory DCs. Herein, the evidence that the potential of regulatory DC the-rapy is considerable and that there are compelling reasons to evaluate it in the setting of organ transplantation in the near future are discussed in this paper. |
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| Keywords: | dendritic cells organ transplantation clinical application |
| 本文献已被 CNKI 维普 万方数据 等数据库收录！ |
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