从原发性肝癌的家族性分布探讨乙型肝炎与其发病关系 |
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引用本文: | 刘玉环,郭继玲,黄玉璞. 从原发性肝癌的家族性分布探讨乙型肝炎与其发病关系[J]. 吉林大学学报(医学版), 1984, 0(3) |
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作者姓名: | 刘玉环 郭继玲 黄玉璞 |
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作者单位: | 白求恩医科大学第一临床学院传染科(刘玉环,郭继玲),双阳县医院内科(黄玉璞) |
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摘 要: | <正> 近年来许多研究表明,乙型病毒性肝炎与原发性肝癌关系极为密切,二者呈家族性分布已早有报道。为进一步探讨二者关系,现将我科遇到的吉林省双阳河公社同一家族中弟兄4人同患原发性肝癌的病例,以及对其家庭及密切接触者所做的调查情况报告如下。
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The relationship between HB and liver carcinoma: A study of familial assembly occurrence of primary liver carcinoma |
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Abstract: | A familial assembly occurrence of primary liver carcinoma is reported in this paper. A patient and his three brothers died of liver carcinoma in seven and a half years.Of the 46 persons who had had close contacts with the patient and his siblings, 21 had hepatomegaly, among whom 7 had anamnestic hepatits; HBsAg was positive in 10 persons (21.7%) , anti-HBc was positive in 13 (38.5%) , HBeAg was positive in 4 (8.7%) ; and abnormality of liver function was found in 5 persons. Evidence presented suggests apparent relationship between HB and liver carcinoma, the principal factor of HB in the occurrence of liver carcinoma, and the assembly occurrence of liver carcinoma in a family. Our results are clear enough to warrant the necessity of controlling HB in the prevention of liver carcinoma. |
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