西酞普兰治疗伴焦虑症状老年高血压的疗效

目的探讨抗抑郁剂西酞普兰治疗伴有焦虑症状的老年高血压患者的临床疗效。方法 63例老年高血压患者,汉密顿焦虑量表（HAMA-14）评分≥14分,随机分为研究组（n=32）与对照组（n=31）,研究组给予降压药物与西酞普兰治疗,对照组只给降压药物治疗。观察8周。结果治疗后两组患者的收缩压、舒张压、HAMA总分均下降,差异有统计学意义（P〈0.05或P〈0.01）。研究组治疗后的收缩压、舒张压、HAMA总分均低于对照组（P〈0.05或P〈0.01）。结论西酞普兰治疗老年高血压患者的焦虑症状疗效肯定,安全性好,适合作为老年患者的首选。

Effect of Citalopram in the treatment of senile hypertension with anxiety symptoms

Objective To investigate the curative effect of antidepressant Citalopram in the treatment of senile hypertensive patients with anxiety symptoms.Methods 63 cases of senile hypertensive patients,with more than 14 points of the Hamilton anxiety scale(HAMA-14) scores,were randomly divided into study group(n = 32) and control group(n = 31).Citalopram and antihypertensive drugs were given to the patients in study group,and the patients in control group were given antihypertensive drug only.Observation was done for 8 weeks.Results The systolic blood pressure,diastolic blood pressure and total score of HAMA of all patients in both groups were significantly decreased after treatment(P < 0.05 or P < 0.01).And the systolic blood pressure,diastolic blood pressure and total score of HAMA of patients in study group were lower than that of control group(P < 0.05 or P < 0.01).Conclusion Citalopram is useful and safe for anxiety symptoms in senile hypertensive patients,it can be the first choice for senile patients.