运动训练联合注射玻璃酸钠与口服氨基葡萄糖治疗34例膝关节骨性关节炎的疗效分析

目的：探讨运动训练联合注射玻璃酸钠与口服氨基葡萄糖治疗膝关节骨性关节炎的疗效。方法：选取膝关节骨性关节炎（KOA）患者68例，随机分为对照组和研究组各34例，对照组患者均给予注射玻璃酸钠联合口服氨基葡萄糖治疗，而研究组患者则在对照组的基础上进行变速变负荷运动训练。比较2组患者的临床疗效和不良反应发生情况。结果：研究组患者的临床疗效为88.23%，显著高于对照组的70.59%（P<0.05）；研究组患者治疗后的VAS疼痛评分和膝关节功能评分分别为（3.52±1.14）分和（81.31±0.74）分，显著优于对照组的（5.43±1.21）分和（68.74±0.87）分（P<0.05）；研究组患者治疗后的生理功能、生理职能、躯体疼痛、总体健康、社会功能、活力、情感职能和精神健康共8个维度的评分均高于对照组（P<0.05）；2组患者治疗期间均未出现严重的不良反应。结论：变速变负荷运动训练联合注射玻璃酸钠与口服氨基葡萄糖治疗KOA可有效改善患者的膝关节功能和生活质量，值得应用于临床。

Effects of athletic training combined with sodium hyaluronate and glucosamine in the treatment of 34 cases of patients with knee osteoarthritis

Objective:To discuss the effects of athletic training combined with sodium hyaluronate and glucosamine in the treatment of patients with knee osteoarthritis (KOA).Methods:Sixty-eight patients with KOA were selected and randomly divided into a control group and a research group with 34 patients each. The control group was treated with sodium hyaluronate and glucosamine while the observation group was additionally treated with athletic training besides the therapies for the control group. The clinical effects and the occurrence of adverse reactions were compared between the two groups before and after treatment. Results:The clinical effectiveness rate was obviously higher in the research group (88.23%) than in the control group (70.59%) (P<0.05). VAS pain scores and Lysholm knee scores were (3.52±1.14) and (81.31±0.74) in the research group and (5.43±1.21) and (68.74±0.87) in the control group after treatment, respectively, which were much better in the research group than in the control group (P<0.05). Eight dimensional scores including physiological and physical function, body pain, general health, social function, dynamic, emotional function and mental health were all higher in the research group than in the control group after treatment (P<0.05). There were no serious adverse reactions occurred in both groups during treatment.Conclusion:Knee function and quality of life of the patients with KOA can be effectively improved by variable velocity and resistance training combined with the injection of sodium hyaluronate and oral administration of glucosamine, which are worthy of application in clinic.