42例子痫前期患者血清学指标与尿蛋白值变化及其临床意义

目的：探讨子痫前期血清学指标与尿蛋白值变化及其临床意义。方法：选取我院产科子痫前期孕妇42例作为研究组，同期选取正常孕妇40例作为对照组，采用ELISA方法检测血清AST、ALT、GGT、TP、ALB、Urea、Cr、UA、b2-MG、LDH和24 h电泳检测尿蛋白UPRO，比较两组上述指标的差异。结果：研究组血清学指标（AST、ALT、GGT、Urea、Cr、UA、b2-MG、LDH）和尿蛋白值均明显高于对照组，血清TP、ALB均明显低于对照组，两组比较均有显著性差异。结论：上述指标可能参与子痫前期病情的发生。

The changes of serological indexes and urinary protein value in 42 cases of patients with preeclampsia and their clinical signiifcance

Objective:To explore the changes of serological indexes and urinary protein value in the patients with preeclampsia and their clinical significance. Methods: Forty-two cases of preeclampsia from our obstetric department were selected as a study group, and meanwhile 40 cases of normal pregnant women as a control group. Serological indexes such as AST, ALT, GGT, TP, ALB, Urea, Cr, UA, b2-MG and LDH, and UPRO value were detected by ELISA and electrophoresis, respectively. Differences of the above mentioned indexes were compared between the two groups. Results: The serological indexes including AST, ALT, GGT, Urea, Cr, UA, b2-MG and LDH and urinary protein value were signiifcantly higher while serum TP and ALB were signiifcantly lower in the study group than in the control group (P<0.05). Conclusion:Those indexes may participate in the occurrence of preeclampsia.