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| 烯丙雌醇治疗黄体功能性不育的临床观察 | |
| 引用本文： | 随笑琳,赵晓徽,李微,王景华.烯丙雌醇治疗黄体功能性不育的临床观察[J].天津医科大学学报,2003,9(2):229-230,269. |
| 作者姓名： | 随笑琳 赵晓徽 李微 王景华 |
| 作者单位： | 1. 天津医科大学总医院妇产科,天津,300052 2. 天津医科大学总医院病理科,天津,300052 3. 天津医科大学总医院神经研究所,天津,300052 |
| 摘 要： | 目的 :观察20例黄体功能性不育的健康妇女应用烯丙雌醇的临床疗效。方法 :对经子宫内膜病理证实为黄体功能不足(LutealPhasedefect,LPD)的受试患者,在分泌早期 (着床窗口期 )采用免疫组化方法检测子宫内膜雌激素受体 (ER)、孕激素受体 (PR)水平并采用放免法观察血清雌二醇 (E2)、孕激素 (P)的动态变化。结果 :与治疗前比较 ,子宫内膜PR和血清E2、P水平有显著性差别(P<0.01) ,而子宫内膜ER无显著性差别(P>0.05)。结论 :烯丙雌醇作为外源性孕激素可以改善黄体功能 ,并具有一定的黄体支持作用 |
| 关 键 词： | 烯丙雌醇 黄体功能不足 子宫内膜 雌激素受体 孕激素受体 |
| 文章编号： | 1006-8147(2003)02-0229-03 |
Clinical observation on turinal treatment of infertile women with iuteal insufficiency |
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| SUI Xiao-lin,ZHAO Xiao-hui,LI Wei,WANG Jing-hua.Clinical observation on turinal treatment of infertile women with iuteal insufficiency[J].Journal of Tianjin Medical University,2003,9(2):229-230,269. | |
| Authors: | SUI Xiao-lin ZHAO Xiao-hui LI Wei WANG Jing-hua |
| Institution: | SUI Xiao-lin1,ZHAO Xiao-hui1,LI Wei2,WANG Jing-hua3 |
| Abstract: | Objective: To investigate the clinical effect of turinal treating 20 infertile women with luteal insufficiency during the earlier luteal phase(after ovulation 7th day).Methods:Patology examination were done on endometrium in 20 cases and determined as luteal insufficiency. Meanwhile,their ER,PR expressions were measured by immunohistochemical method and E2,P levels were measured by radiaimmunity method.Results:In after-treatment group,their PR,E2,P levels were significantly than in before-treatment group(P<0.01);their ER levels had no significantly(P>0.05).Conclusion:Turinal may improve luteal function as external progesterone and was validity of infertile women of luteal insufficiency. |
| Keywords: | Turinal Luteal phase defect Endometrium Estrogen receptor Progesterone receptor |
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