"铁、Vitc、叶酸"速溶冲剂对学龄前儿童缺铁性贫血的干预研究

目的：调查儿童缺铁性贫血（IDA）检出了解,了解儿童IDA红细胞铁蛋白（EF）及血清蛋白（SF）改变的相关性及其意义,观察“铁、Vitc、叶酸速溶冲剂”以IDA患儿的疗效。方法 2950名学龄前儿童接受体检和Hb检测;按全国统一标准计算缺铁性贫血检出率。按照随机原则选择102名患儿分为A,B,C三组,A,B两组投以“铁、Vitc、叶酸速溶冲剂”,疗程分别为12周和6周,C组为对照组,同时设立正常对照组。各组患儿均于治疗前后采血检测HB,ZPP,SF,EF。结果 （1）学龄前儿童缺铁性贫血检出率为26．27％,其中2岁组检出率高达29．85％;（2）贫血患儿治疗前后SF与EF均呈正相关关系。（3）应用“铁、Vitc、叶酸速溶冲剂”治疗IDA,患儿症状改善显著,无副作用。结论：学龄前儿童贫血的检出率为26．7％;EF对IDA的治疗反应按SF敏感,可作为治疗IDA早期疗效评价指标;“铁、Vitc、叶酸速溶叶剂”治疗IDA具有依从性好,疗效确切,无副作用及服用方便等,值得进一步推广应用。

Investigate the Incidence Rate of Anemia in Preschool Aged Children and Intervention to Iron Deficiency Anemia With ICFQP

To investigat the incidence rate of anemia in preschooler find out the changes of serum ferritin (SF) and erythrocyte ferritin (EF) and relationship between SF and EF in iron deficiency anemia (IDA), observe the treatment effect of new medicine "lron-vitamin C-Folic acid" quick-dissolved preparation (ICFQP) for IDA. 2950 preschool aged children were examined. Using the national standard to diagnose anemia, the incidence rate of anemia was calculated. 102 IDA chosen randomly were divided into group A,B and C. Group A and B received ICFQP for treating IDA. Group C was control. The Hb,ZPP, SF, EF. were examined in all groups by micromethod.The incidence rate of anemia was 26.27% in its area. The levels of EF in IDA was significantly higher than that normal controls (P<0.01). EF was positively related to SF. The ICFQP to treat IDA has good effects and no side effects. [Conclusions]The incidence rate of anemia at its area was higher than that recently reported. EF was regarded as an evaluated target in treating IDA. ICFQP to treat IDA has good conformability high effect, more convenience and has no side effects.