| 应用动态血糖监测系统评价甘精胰岛素作为基础胰岛素治疗的优越性 |
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| 引用本文： | 王先令,陆菊明,潘长玉,母义明,窦京涛,巴建明.应用动态血糖监测系统评价甘精胰岛素作为基础胰岛素治疗的优越性[J].中华内分泌代谢杂志,2006,22(4):319-321. |
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| 作者姓名： | 王先令 陆菊明 潘长玉 母义明 窦京涛 巴建明 |
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| 作者单位： | 100853,北京,解放军总医院内分泌科 |
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| 基金项目： | 军队十五重点课题（0172133） |
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| 摘 要： | 采用动态血糖监测系统比较磺脲类药物治疗效果不佳的2型糖尿病患者睡前联合甘精胰岛素或中性鱼精蛋白锌胰岛素（NPH）治疗12周后血糖谱的变化。结果显示，联合甘精胰岛素治疗，在空腹血糖达到同样较好控制的同时，夜间低血糖发生率低，全天血糖曲线波动小。
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| 关 键 词： | 动态血糖监测系统 糖尿病 2型 甘精胰岛素 |
| 收稿时间： | 2005-08-12 |
| 修稿时间： | 2005年8月12日 |
Evaluation of the superiority of glargine as basal insulin replacement by continuous glucose monitoring system |
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| WANG Xian-ling,LU Ju-ming,PAN Chang-yu,MU Yi-ming,DOU Jing-tao,BA Jian-ming.Evaluation of the superiority of glargine as basal insulin replacement by continuous glucose monitoring system[J].Chinese Journal of Endocrinology and Metabolism,2006,22(4):319-321. |
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| Authors: | WANG Xian-ling LU Ju-ming PAN Chang-yu MU Yi-ming DOU Jing-tao BA Jian-ming |
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| Institution: | Department of Endocrinology, Chinese PLA General Hospital, Beijing 100853 |
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| Abstract: | With the continuous glucose monitoring system, daily blood glucose profiles were compared in type 2 diabetic patients treated with glargine or neutral protamine hagedorn (NPH) at bedtime for 12 weeks. The blood glucose levels in these patients were previously not well controlled with sulfonylureas. The results suggested that combined treatment with glargine before bedtime showed less nocturnal hypoglycemia and more stable blood glucose profile with less excursion when fasting blood glucose levels were well controlled. |
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| Keywords: | Continuous glucose monitoring system Diabetes mellitus type 2 Glargine |
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