地尔硫静脉滴注治疗冠心病优于丹参注射液

目的：比较地尔硫与丹参注射液静脉滴注（静滴）治疗冠心病的疗效。方法：冠心病８６例分为２组，地尔硫组４６例（男性２９例，女性１７例；年龄６２ａ±ｓ９ａ）用地尔硫注射液５０ｍｇ加入５％葡萄糖注射液２５０ｍＬ中静滴，ｑｄ×１０ｄ；丹参组４０例（男性２７例，女性１３例；年龄５８ａ±８ａ）用丹参注射液１６ｍＬ加入５％葡萄糖注射液２５０ｍＬ中静脉滴注，ｑｄ×１０ｄ。结果：地尔硫组与丹参组症状总有效率分别为６１％与３８％（Ｐ＜０．０１）；心电图总有效率分别为６１％与２８％（Ｐ＜０．０１）。地尔硫组对表示心肌缺血范围和程度的ＮＳＴ，ΣＳＴ及左室功能的ＳＶ，ＣＯ，ＥＦ改善均有显著意义（Ｐ＜０．０５），丹参组则无。结论：地尔硫治疗冠心病优于丹参。

Intravenous drip of diltiazem is better than Salvia miltiorrhiza injection drip in treating coronary disease

AIM: To compare the effects of iv drips of diltiazem and Salvia miltiorrhiza on coronary disease. METHODS: Eighty_six patients were divided into 2 groups: 46 patients (M 29, F 17; age 62 a±s 9 a) were treated with diltiazem 50 mg in 5% glucose injection 250 mL, iv, drip, qd for 10 d; 40 patients (M 27, F 13; age 58 a±8 a) were treated with Salvia miltiorrhiza injection 16 mL, in 5% glucose injection 250 mL iv, drip qd for 10 d. RESULTS: The total responsive rate in diltiazem group in symptoms (96%) was higher than that in Salvia miltiorrhiza group (38%, P<0.01); The total responsive rates on the electrocardiogram were 61% in diltiazem group and 28% in Salvia miltiorrhiza group (P<0.05); Diltiazem improved obviously NST, ΣST and SV, CO, LVEF of ventricular function (P<0.05). CONCLUSION: The efficacy of diltiazem is better than that of Salvia miltiorrhiza on coronary heart disease