Effect of angiotensin II and atrial natriuretic factor on neurons in the subfornical organ of ducks and rats in vitro |
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| Authors: | Herbert A. Schmid Eckhart Simon |
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| Affiliation: | Max-Planck-Institut für physiologische und klinische Forschung, W.G. Kerckhoff-Institut, Bad Nauheim, FRG. |
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| Abstract: | Atrial natriuretic factor (ANF) antagonizes many angiotensin II (ANGII)-induced effects on osmoregulatory relevant parameters in vivo. In this study ANF analogues decreased the spontaneous and the ANGII-induced electrical activity of subfornical organ (SFO) neurons in rats, but had no effect on ANGII sensitive or insensitive SFO neurons in ducks. These results suggest a more distinct functional separation for the responsiveness to ANGII and ANF in birds compared to mammals. |
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| Keywords: | Osmoregulation Duck Rat Subfornical organ Angiotensin II Atrial natriuretic factor Neuron In vitro Slice Electrophysiology |
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