Mosaic pattern of encapsulated hepatocellular carcinoma: Correlation of magnetic resonance imaging and pathology |
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| Authors: | Byung Ihn Choi M.D. Geon Kook Lee Soo Tae Kim Man Chung Han |
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| Affiliation: | (1) Department of Radiology, College of Medicine, Seoul National University, Seoul, Korea;(2) Department of Pathology, College of Medicine, Seoul National University, Seoul, Korea;(3) Department of Surgery, College of Medicine, Seoul National University, Seoul, Korea |
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| Abstract: | Internal architecture of an encapsulated hepatocellular carcinoma (HCC) was studied with magnetic resonance imaging and histologic correlation. The capsule of HCC showed low intensity relative to liver on both T1- and T2-weighted images. The T1-weighted images were superior to the T2-weighted images in delineating the capsule of HCC. The tumor showed a mosaic pattern, which was a configuration composed of multiple compartments of different intensities, reflecting viable tumor nodules and a necrotic portion. Viable tumor nodules, composed of trabeculae of polygonal cells resembling the normal liver cell with well-formed sinusoids, showed low intensity relative to liver on T1-weighted images and high intensity on T2-weighted images. The necrotic portion, composed of coagulation of amorphous, thick eosinophilic material without hemorrhage or inflammatory reaction, showed low intensity relative to liver on both T1- and T2-weighted images. The T2-weighted images were superior to the T1-weighted images in demonstrating the mosaic pattern of HCC. |
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| Keywords: | Liver, neoplasms Hepatocellular carcinoma Magnetic resonance imaging |
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