侵袭性垂体腺瘤的伽玛刀治疗

目的 探讨伽玛刀治疗侵袭性垂体腺瘤的疗效。方法对临床确诊的126例侵袭性垂体腺瘤病人行Siemens Symphony1．5TMR扫描定位，应用Elekta TPS设计治疗规划，采用Leksell-B型伽玛刀实施治疗。结果随访4。99个月。影像学检查显示肿瘤控制率为95．2％（120例），临床症状改善率为92．9％（117例），内分泌改善率为91．7％（33例），复发率为0．8％（1例）。无远期并发症。结论伽玛刀可作为侵袭性垂体腺瘤的首选治疗方法，疗效较好。

Gamma knife radiosurgery for invasive pituitary adenoma

Objective To explore the result of Gamma knife radiosurgery for invasive pituitary. Methods One hundred and twenty-six cases of invasive pituitary adenoma were located by Siemens Symphony 1.5 T MR, then treated by Leksell-B type Gamma knife unit. Results All the patients had a follow-up of 4-99 months respectively. The tumor control rate was 95.2% （120 cases）, clinical symptom improvement rate was 92.9% （117 cases）, endocrine improvement rate 91.7% （33 cases）, and the recurrence rate 0.8% （1 case）. No complication occurred. Conclusion Gamma knife radiosurgery can be the first choice of the invasive pituitary adenoma, and may have good therapeutic effect.