| 乳腺癌患者外周血中hMAM、SBEM和CEACAM19 mRNA联合检测及其临床意义 |
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| 引用本文： | 于秀艳,李铤,丛占杰,王文龙,张晓伟,吴雪峰. 乳腺癌患者外周血中hMAM、SBEM和CEACAM19 mRNA联合检测及其临床意义[J]. 吉林大学学报(医学版), 2022, 48(1): 195-202. DOI: 10.13481/j.1671-587X.20220124 |
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| 作者姓名： | 于秀艳 李铤 丛占杰 王文龙 张晓伟 吴雪峰 |
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| 作者单位： | 吉林省肿瘤医院检验科，吉林 长春 130012 |
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| 基金项目： | 吉林省卫计委卫生与健康技术创新项目(2018J025) |
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| 摘 要： | 目的:探讨外周血中人乳腺珠蛋白(hMAM)、乳腺小黏蛋白(SBEM)和癌胚抗原相关黏附因子19(CEACAM19)mRNA联合检测在乳腺癌诊断中的作用,阐明其临床意义.方法:收集104例乳腺癌患者(乳腺癌组)、52例乳腺良性病变患者(良性乳腺病组)和50名健康人(健康对照组)的外周血,采用实时荧光定量PCR(RT-qP...
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| 关 键 词： | 乳腺肿瘤 微转移 人乳腺珠蛋白 乳腺上皮小黏蛋白 癌胚抗原相关黏附因子19 |
| 收稿时间： | 2021-07-18 |
Combined detection of hMAM,SBEM and CEACAM19 mRNA in peripheral blood of breast cancer patients and its clinical significance |
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| YU Xiuyan,LI Ting,CONG Zhanjie,WANG Wenlong,ZHANG Xiaowei,WU Xuefeng. Combined detection of hMAM,SBEM and CEACAM19 mRNA in peripheral blood of breast cancer patients and its clinical significance[J]. Journal of Jilin University: Med Ed, 2022, 48(1): 195-202. DOI: 10.13481/j.1671-587X.20220124 |
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| Authors: | YU Xiuyan LI Ting CONG Zhanjie WANG Wenlong ZHANG Xiaowei WU Xuefeng |
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| Affiliation: | Department of Clinical Laboratory，Jilin Provincial Tumor Hospital，Changchun 130012，China |
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| Abstract: | ObjectiveTo investigate the effect of combined detection of the biomarkers human mammaglobin （hMAM）， small breast epithelial mucin （SBEM） and carcino-embryonic antigen related adhesion molecule 19 （CEACAM19） mRNA in the diagnosis of breast cancer， and to clarify its clinical significance. |
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| Keywords: | Breast neoplasms Micrometastases Human mammaglobin Small breast epithelial mucin Carcino-embryonic antigen related adhesion molecule 19 |
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