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In vitro PAI-1 inhibitory activity of oxalamide derivatives |
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| Authors: | Jain Mukul R Shetty Shankar Chakrabarti Ganes Pandya Vrajesh Sharma Ajay Parmar Bhavesh Srivastava Soma Raviya Mehul Soni Hitesh Patel Pankaj R |
| Institution: | Zydus Research Centre, Sarkhej-Bavla NH No. 8A, Moraiya, Ahmedabad-382210, Gujarat, India. mukul.jain@zyduscadila.com |
| Abstract: | A number of oxalamide derivatives have been synthesized and evaluated for PAI-1 inhibitory activity. In vitro PAI-1 inhibitory activities of oxalamide derivatives are evaluated by chromogenic assay. Few compounds have shown significant PAI-1 inhibitory activity. |
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