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西红花多甙片治疗冠心病心绞痛多中心临床研究
引用本文:刘宇,顾仁樾,胡婉英,刘玉秀. 西红花多甙片治疗冠心病心绞痛多中心临床研究[J]. 中西医结合心脑血管病杂志, 2005, 3(7): 573-574
作者姓名:刘宇  顾仁樾  胡婉英  刘玉秀
作者单位:1. 上海中医药大学附属龙华医院
2. 上海中医药大学附属曙光医院
3. 中国人民解放军南京军区总院
摘    要:目的观察西红花多甙片治疗冠心病心绞痛(胸痹心血瘀阻型)的临床疗效和安全性.方法采用随机、阳性药对照、多中心临床观察,按1∶1比例随机分为治疗组88例,给予西红花多甙片(4粒,每日3次),对照组87例,给予地奥心血康胶囊(2粒,每日3次).28 d后进行胸痹症状、心电图、中医证候等疗效及毒副反应的评估.结果治疗组能明显改善胸痹症状,心电图疗效总有效率68.18%,并能明显改善中医证候疗效,在改善胸痹症状、中医证候疗效治疗组优于对照组(P<0.01).结论西红花多甙片是治疗冠心病心绞痛安全、有效的药物.

关 键 词:西红花多甙片  冠心病心绞痛  地奥心血康
文章编号:1672-1349(2005)07-0573-02
修稿时间:2004-06-02

The Treatment of Angina Pectoris by Glycosides of Saffron Crocus (Crocus Sativus L):A Randomized, Active-controlled, Multi-center Trial
Liu Yu,Gu Renyue,Hu Wanying,et al Longhua Hospital,Shanghai University of TCM. The Treatment of Angina Pectoris by Glycosides of Saffron Crocus (Crocus Sativus L):A Randomized, Active-controlled, Multi-center Trial[J]. Chinese Journal of Integrative Medicine on Cardio-/Cerebrovascular Disease, 2005, 3(7): 573-574
Authors:Liu Yu  Gu Renyue  Hu Wanying  et al Longhua Hospital  Shanghai University of TCM
Affiliation:Shanghai 200032
Abstract:Objective To assess the therapeutic efficiency and safety of glycosides of saffron crocus (crocus sativus L) for treatment of angina pectoris.Methods One hundred and Seventy -six patients with Angina Pectoris were randomly divided into the treatment group treated with g1ycosides of saffron crocus and the control group treated with Diaoxinxuekang capsules.The therapeutic course was 28 days. Main symptoms and signs,ECG,side-effect and toxic responses were observed pre- and post-therapy.Results Following the therapy with glycosides of saffron crocus,the symptoms,signs and clinical effects were improved significantly.There was a significant difference in two groups(P<0.01).The total effective rate by ECG was 68.18% in glycosides of saffron crocus group.Conclusion The results suggest that glycosides of saffron crocus is effective and save for treatment of angina pectoris.
Keywords:glycosides of saffron crocus  angina pectoris  Diaoxinxuekang
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