高尿酸并高甘油三酯血症鹌鹑血液流变学的变化及菊苣提取物N2对其的影响

目的观察高尿酸并高甘油三酯血症状况下血液流变学和纤溶活性的变化,同时观察菊苣提取物N2对模型血液流变学和纤溶活性的影响.方法用酵母塑造高尿酸并高甘油三酯血症鹌鹑模型,观察模型血液流变学和纤溶活性的变化及菊苣提取物N2对其的影响.结果实验性高尿酸并高甘油三酯血症鹌鹑血液流变学和纤溶活性出现明显异常,菊苣提取物N2可显著改善高尿酸并高甘油三酯血症鹌鹑的血液流变性和纤溶系统活性.结论高尿酸并高甘油三酯血症病理情况下的血液流变学会出现明显异常,菊苣提取物N2对其有逆转作用.

Changes in the Blood Rheology in the Partridge with Hyperuricemia plus Hypertriglyceridemia:Effects of Chicory Extract N2

Objective To observe the changes in the blood rhenology and the fibrinolytic activity in the condition of hyperuricemia plus hypertriglyceridemia, and to investigate the effects of Chicory Extract N2 (CE-N2) on the blood rhenology and the fibrinolytic activity in the model of hyperuricemia plus hypertriglyceridemia. Method Yeast was used to establish the partridge model of hyperuricemia plus hypertriglyceridemia, in which the changes in the blood rheno-logy and the fibrinolytic activity, and the effects of CE-N2 were observed. Results It was found that the criteria of blood rheology and fibrinolytic activity became obviously abnormal in the model, and CE-N2 could markedly improve the state of blood rheology and the activity of fibrinolytic system.Conclusion The criteria of blood rheology may become obviously abnormal in the condition of hyperuricemia plus hypertriglyceridemia, and CE-N2 can reverse the abnormality.