肝硬化合并皮肤软组织感染研究进展

肝硬化患者因其免疫力低下、下肢水肿等原因是皮肤软组织感染的高危人群，常见的皮肤软组织感染部位为下肢，常见的感染类型为蜂窝织炎。与一般人群不同，肝硬化患者合并皮肤软组织感染的病原体以革兰阴性杆菌为主。血清肌酐值和MELD评分为肝硬化患者合并皮肤软组织感染预后不良的预测因素。我国肝硬化患者合并皮肤软组织的病原学与临床特征尚需进一步明确，旨在为优化此类患者的优化管理提供一定的依据。

Progress on skin and soft tissue infections in patients with liver cirrhosis

Patients with liver cirrhosis are in high risk of skin and soft tissue infections for the compromised immune and edema of lower extremity. Lower extremity is the most common position for skin and soft tissue infection for patients with liver cirrhosis. Cellulitis is the most common type of skin and soft tissue infections for these patients. Gram-negative bacillus are the major pathogens for cirrhosis patients with skin and soft tissue infections, which are different from general population. Serum creatinine level and MELD score are prognosis predictors for these patients. Further studies should be carried out to identify the pathogen, clinical characteristics of skin and soft tissue infections in Chinese patients with liver cirrhosis, in order to provide certain basis for optimizing the management of these patients.