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正交设计优化肉苁蓉中麦角甾苷提取工艺
引用本文:杨建宏,李治芳,孙磊,陈欢. 正交设计优化肉苁蓉中麦角甾苷提取工艺[J]. 辽宁中医杂志, 2010, 0(5): 891-892
作者姓名:杨建宏  李治芳  孙磊  陈欢
作者单位:宁夏医科大学药学系;
基金项目:宁夏自然基金项目(NZ0653)
摘    要:目的:优选肉苁蓉最佳提取工艺。方法:根据肉苁蓉中各药物化学成分及药理作用,在单因素考察影响提取物出膏率和有效成分含量基础上,采用正交试验设计,以提取物麦角甾苷含量为考察指标,对影响麦角甾苷提取因素的工艺溶剂乙醇浓度、液料比及提取时间进行试验。结果:最佳提取工艺为药材中加入10倍量60%的乙醇回流提取,提取2h。结论:该工艺下的肉苁蓉中麦角甾苷含量提取可达0.397%。

关 键 词:肉苁蓉  麦角甾苷  正交设计  提取工艺

Acteoside Extracting Method from Cistanche Deserticol by Ethanol
YANG Jian-hong,LI Zhi-fang,SUN Lei,CHEN Huan. Acteoside Extracting Method from Cistanche Deserticol by Ethanol[J]. Liaoning Journal of Traditional Chinese Medicine, 2010, 0(5): 891-892
Authors:YANG Jian-hong  LI Zhi-fang  SUN Lei  CHEN Huan
Affiliation:Ningxia Medical University/a>;Yinchuan 750004/a>;Ningxia/a>;China
Abstract:Objective:The technology of extracting Acteoside by ethanol from Cistanche deserticol was studied in this article.Methods:The optimum extraction conditions were investigated by orthogonal test.Results:The optimal extraction process is as follows:phase ratio of solid to liquid(g∶mL) of 1∶10 extraction time of 2 h,ethanol to whole extraction system in volume of 60%.Conclusion:The extraction yield reached 0.397%.
Keywords:cistanche deserticol  acteoside  orthogonal method  extraction method  
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