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| 低频重复经颅磁刺激治疗精神分裂症顽固性幻听的随机双盲对照研究 | |
| 引用本文： | 任艳萍,周东丰,蔡焯基,黄青,卢苓,陈琦.低频重复经颅磁刺激治疗精神分裂症顽固性幻听的随机双盲对照研究[J].中国心理卫生杂志,2010,24(3). |
| 作者姓名： | 任艳萍 周东丰 蔡焯基 黄青 卢苓 陈琦 |
| 作者单位： | 1. 北京大学精神卫生研究所,卫生部精神卫生学重点实验室(北京大学),北京,100191;首都医科大学附属北京安定医院,北京,100088 2. 北京大学精神卫生研究所,卫生部精神卫生学重点实验室(北京大学),北京,100191 3. 首都医科大学附属北京安定医院,北京,100088 |
| 摘 要： | 目的:初步探讨双背侧前额叶低频重复经颅磁刺激(rTMS)治疗精神分裂症顽固性幻听的疗效和安全性,并观察其副反应。方法:25例伴顽固性幻听的精神分裂症患者随机分为rTMS治疗组(N=12)和对照组(N=13),分别给予10次1HzrTMS真刺激和伪刺激治疗,治疗期间维持原有抗精神病药种类及剂量不变。采用阳性和阴性症状量表(Positive and Negative Syndrome Scale,PANSS)评定临床症状,采用治疗中需处理的不良反应症状量表(Treatment Emergent Symptom Scale,TESS)等检查评估副反应。结果:25例患者均完成治疗,治疗组有效率高于对照组(75%vs.31%,P0.05)。未观察到明显副反应。结论:1Hz双背侧前额叶低频重复经颅磁刺激治疗精神分裂症顽固性幻听可能有效,且安全性好,值得进一步研究。 |
| 关 键 词： | 重复经颅磁刺激 精神分裂症 幻听 随机对照研究 |
Treatment with 1Hz repetitive transcranial magnetive stimulation in auditory hallucination of schizophrenia:A double blind,randomized controlled trial |
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| REN Yan-Ping,ZHOU Dong-Feng,CAI Zhuo-Ji,HUANG Qing,LU Ling,CHEN Qi.Treatment with 1Hz repetitive transcranial magnetive stimulation in auditory hallucination of schizophrenia:A double blind,randomized controlled trial[J].Chinese Mental Health Journal,2010,24(3). | |
| Authors: | REN Yan-Ping ZHOU Dong-Feng CAI Zhuo-Ji HUANG Qing LU Ling CHEN Qi |
| Institution: | REN Yan-Ping1,2,ZHOU Dong-Feng2,CAI Zhuo-Ji1,HUANG Qing1,LU Ling1,CHEN Qi11Institute of Mental Health,Peking University,Key Laboratory of Mental Health,Ministry of Health (Peking University),Beijing 100191,China2Beijing ,ing Hospital,Capital Medical University,Beijing 100088,China |
| Abstract: | Objective:To examine the therapeutic effects of dual dorsolateral prefrontal repetitive transcranial magnetic stimulation(rTMS)on auditory hallucinations experienced by schizophrenic patients.Methods:A double-blind randomized controlled study was conducted.Totally 25 schizophrenic patients met DSM-IV criteria for schizophrenia and had anditory hallucination with stable antipsychotic drugs treatment were recruited.Subjects were grouped into active treatment subgroup and sham subgroup randomly.Measurements in... |
| Keywords: | schizophrenia auditory hallucination repetitive transcranial magnetic stimulation (rTMS) randomized controlled trial |
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