| 山栀茶中一个新的三萜类化合物 |
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| 作者姓名： | Xiao BK Wang WL Huang RQ Yang JY Dong JX |
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| 作者单位： | 军事医学科学院放射与辐射医学研究所;解放军总医院药品保障中心; |
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| 基金项目： | 国家自然科学基金资助项目(81072613) |
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| 摘 要： | 为了研究山栀茶(Radix Pittospori)的化学成分,运用多种色谱方法进行分离纯化,从其氯仿提取物中分离得到2个三萜类化合物,并根据理化性质和波谱数据鉴定其结构分别为22-acetyl-21-(2-acetoxy-2-methylbutanoyl)-R1-barrigenol(1)和3α-hydroxyl-20-demethylisoaleuritolic-14(15)-ene-28,30-dioic acid(2)。其中,化合物1为新的三萜类化合物,化合物2为首次从该植物中分离得到。
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| 关 键 词： | 山栀茶 三萜 22-acetyl-21-(2-acetoxy-2-methylbutanoyl)-R1-barrigenol |
A new triterpenoid fom Radix Pittospori |
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| Xiao BK,Wang WL,Huang RQ,Yang JY,Dong JX.A new triterpenoid fom Radix Pittospori[J].Acta Pharmaceutica Sinica,2011,46(9):1101-1103. |
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| Authors: | Xiao Bing-kun Wang Wei-lan Huang Rong-qing Yang Jian-yun Dong Jun-xing |
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| Institution: | XIAO Bing-kun 1,WANG Wei-lan 2,HUANG Rong-qing 1,YANG Jian-yun 1,DONG Jun-xing 1 (1.Institute of Radiation Medicine,Academy of Military Medical Sciences,Beijing 100850,China,2.Department of Pharmaceutical Care,Chinese PLA General Hospital,Beijing 100853,China) |
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| Abstract: | To investigate chemical constituents from Radix Pittospori, chloroform extract of the roots was subjected to column chromatography with various chromatographic techniques. The structures were elucidated on the basis of physico-chemical property and spectral analysis. Two triterpenoids were identified as 22-acetyl-21-(2-acetoxy-2-methylbutanoyl)-R1-barrigenol(1) and 3alpha-hydroxyl-20-demethylisoaleuritolic-14(15)-ene-28, 30-dioic acid (2). Compound 1 is a new triterpene and compound 2 is isolated from this plant for the first time. |
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| Keywords: | Radix Pittospori triterpenoid 22-acetyl-21-(2-acetoxy-2-methylbutanoyl)-R 1-barrigenol |
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