| DHA复合物诱导人胃癌细胞SGC-7901凋亡的实验研究 |
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| 引用本文： | 褚遵华,程东,韩晓英. DHA复合物诱导人胃癌细胞SGC-7901凋亡的实验研究[J]. 预防医学论坛, 2011, 0(11): 1016-1017 |
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| 作者姓名： | 褚遵华 程东 韩晓英 |
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| 作者单位： | 山东省疾病预防控制中心;山东师范大学; |
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| 摘 要： | [目的]研究DHA复合物抗肿瘤作用机理。[方法]以人胃癌细胞SGC-7901为模型,利用吖啶橙染色,荧光显微镜观察人胃癌细胞SGC-7901经DHA复合物治疗前后的形态,研究DHA复合物诱导人胃癌细胞SGC-7901的凋亡作用。[结果]实验发现:经DHA复合物治疗后,人胃癌细胞SGC-7901细胞核出现明显的凋亡核形态。[结论]DHA复合物具有明显诱导人胃癌细胞SGC-7901发生凋亡的作用。
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| 关 键 词： | 二十二碳六烯酸(DHA) 人胃癌细胞SGC-7901 吖啶橙染色 |
Study on DHA Compound Inducing Apoptosis of Human Gastric Carcinoma Cells SGC-7901 |
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| CHU Zun-hua,CHENG Dong,HAN Xiao-ying,et al.. Study on DHA Compound Inducing Apoptosis of Human Gastric Carcinoma Cells SGC-7901[J]. Preventive Medicine Tribune, 2011, 0(11): 1016-1017 |
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| Authors: | CHU Zun-hua CHENG Dong HAN Xiao-ying et al. |
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| Affiliation: | CHU Zun-hua,CHENG Dong,HAN Xiao-ying,et al.(Shandong Center for Disease Control and Prevention,Jinan,250014,Shandong,China) |
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| Abstract: | [Objective]To study the anti-tumor mechanism of DHA compound.[Methods]The cells were strained by acridine orange to explore the apoptosis induced by DHA compound in human gastric carcinoma cells SGC-7901.[Results]The number of apoptotic nucleolus in the group treated with DHA compound was larger than that in negative group.[Conclusion]DHA compound can induce the apoptosis in human gastric carcinoma cells SGC-7901. |
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| Keywords: | Docosahexaenoic acid (DHA) Human gastric carcinoma cells SGC-7901 Acridine orange staining |
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