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复方丹参滴丸在肾移植术后早期应用的临床研究
引用本文:陈益荣,黄赤兵,范明齐,王平贤,冯嘉瑜,肖亚. 复方丹参滴丸在肾移植术后早期应用的临床研究[J]. 中国药业, 2011, 20(11): 7-9
作者姓名:陈益荣  黄赤兵  范明齐  王平贤  冯嘉瑜  肖亚
作者单位:中国人民解放军第三军医大学第二附属医院泌尿外二科,重庆,400037
摘    要:目的 探讨复方丹参滴丸对移植肾功能恢复的影响.方法 将78例肾移植术后患者随机分为治疗组40例和对照组38例,均行常规抗排异治疗,治疗组加用复方丹参滴丸(规格27 mg/丸)10丸/次,3次/d,疗程6个月,比较两组患者治疗前后的血清肌酐、血尿素氮、内生肌酐清除率、24h尿总蛋白、尿N-乙酰-β-D氨基葡萄糖苷酶水平.结果 治疗6个月后,两组患者各项指标较治疗前明显改善(P<0.05);治疗后治疗组血清肌酐、24 h尿总蛋白和尿N-乙酰-β-D氨基葡萄糖苷酶均较对照组明显下降(P<0.05),内生肌酐清除率较对照组明显上升(P<0.05).结论 肾移植术后在常规抗排异治疗基础上加用复方丹参滴丸,能明显改善患者的移植肾功能,并对移植肾功能有较好的保护作用.

关 键 词:肾移植  复方丹参滴丸  肾功能

Effect Observation on Early Application of Compound Danshen Dropping Pills after Renal Transplantation
Chen Yirong,Huang Chibing,Fan Mingqi,Wang Pingxian,Feng Jiayu,Xiao Ya. Effect Observation on Early Application of Compound Danshen Dropping Pills after Renal Transplantation[J]. China Pharmaceuticals, 2011, 20(11): 7-9
Authors:Chen Yirong  Huang Chibing  Fan Mingqi  Wang Pingxian  Feng Jiayu  Xiao Ya
Affiliation:Chen Yirong,Huang Chibing,Fan Mingqi,Wang Pingxian,Feng Jiayu,Xiao Ya(Department of Urology,Second Affiliated Hospital,Third Military Medical University,Chongqing,China 400037)
Abstract:Objective To assess whether Compound Danshen Dropping Pills(CDDP) has the effect on accelerating recovery of renal transplant recipients.Methods Seventy-eight renal transplant recipients were randomly divided into two groups.Forty patients in early stage after renal transplantation were allocated in the treatment group and were added with CDDP(27 mg/pill,10 pills/time,three times a day) on the basis of conventional treatment for six months.And other 38 renal recipients were allocated in the control group an...
Keywords:renal transplantation  Compound Danshen Dropping Pills  renal function  
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