| 氟康唑片粉末压片工艺研究及溶出度测定 |
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| 引用本文： | 刘海蓉. 氟康唑片粉末压片工艺研究及溶出度测定[J]. 中国药业, 2011, 20(8): 46-48 |
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| 作者姓名： | 刘海蓉 |
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| 作者单位： | 南京大学口腔医学院·南京市口腔医院,江苏,南京,210008 |
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| 摘 要： | 目的 对氟康唑片粉末压片工艺进行研究,以提高氟康唑的稳定性和溶出度.方法采用粉末直接压片工艺制备,选择适合粉末直接压片的辅料制备片剂.结果经溶出度测定,制剂可达到药典中氟康唑的溶出度要求,初步稳定性研究表明样品稳定性较好.结论粉末压工艺制备的氟康唑片稳定性好,溶出度符合各项要求.
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| 关 键 词： | 氟康唑 粉末压片 溶出度 |
Powder Compressing Technology of Fluconazole Tablet and Its Dissolution Test |
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| Liu Hairong. Powder Compressing Technology of Fluconazole Tablet and Its Dissolution Test[J]. China Pharmaceuticals, 2011, 20(8): 46-48 |
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| Authors: | Liu Hairong |
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| Affiliation: | Liu Hairong(College of Stomatology,Nanjing University.Nanjing Stomatological Hospital.Nanjing,Jiangsu,China 210008) |
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| Abstract: | Objective To improve the dissolution and stability of fluconazole,the direct powder ompressing technology was used.Some suitable adjuvants were used to prepare the tablet.By detecting the dissolution of Fluconazole Tablets,the preparation met the criterion of the Chinese Pharmacopoeia.The stability of the preparation was studied,and the results showed that the product was stable. |
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| Keywords: | fluconazole powder compressing glyceryl behenate |
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