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Metabolic clearance rate of dehydroisoandrosterone sulfate. VI. Studies of eclampsia.
Authors:N F Gant  J D Madden  S Chand  R J Worley  P K Siiteri  P C MacDonald
Abstract:The metabolic clearance rate of dehydroisoandrosterone sulfate (MCRDS) was measured in 11 women during an eclamptic episode, and the subjects were then followed for at least 5 years. The MCRDS was usually decreased in primigravid women with eclampsia. However, in eclamptic primigravid women who later developed essential hypertension and/or recurrent hypertension in subsequent pregnancies the MCRDS was elevated. Also, in multiparous women with chronic essential hypertension plus superimposed eclampsia, the MCRDS was increased to above normal values.
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