| 重组人促甲状腺激素在甲状腺疾病诊治中的应用 |
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| 引用本文： | 关海霞,陆汉魁. 重组人促甲状腺激素在甲状腺疾病诊治中的应用[J]. 中华核医学杂志, 2012, 32(4): 311-314 |
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| 作者姓名： | 关海霞 陆汉魁 |
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| 作者单位： | 1. 中国医科大学附属第一医院内分泌科、内分泌研究所、辽宁省内分泌疾病重点实验室, 沈阳,110001
2. 上海交通大学附属第六人民医院核医学科 |
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| 基金项目： | 国家自然科学基金（30801120） |
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| 摘 要： | 重组人TSH (rhTSH)于1998年在国外进入临床应用,其临床适应证由辅助DTC患者的随访检查和检测逐渐扩展到辅助131I清除手术后残留甲状腺组织.近期研究表明,rhTSH在辅助131I治疗DTC转移灶、辅助131I治疗非毒性结节性甲状腺肿、提高18F-FDG PET对甲状腺癌的诊断效能及对先天性甲状腺功能减退症的病因鉴别诊断等多方面亦有应用潜力.
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| 关 键 词： | 促甲状腺激素 重组 甲状腺疾病 发展趋势 |
Utility of recombinant human thyrotropin in the management of thyroid diseases |
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| GUAN Hai-xia , LU Han-kui. Utility of recombinant human thyrotropin in the management of thyroid diseases[J]. Chinese Journal of Nuclear Medicine, 2012, 32(4): 311-314 |
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| Authors: | GUAN Hai-xia LU Han-kui |
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| Affiliation: | . Department of Endocrinology and Metabolism, Institute of Endocrinology, Liaoning Key Labo- ratory of Endocrine Diseases, the First Affiliated Hospital of China Medical University, Shenyang 110001, China |
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| Abstract: | Recombinant human TSH （rhTSH） was introduced into clinical practice in 1998. The initial clinical application of rhTSH in facilitating follow-up studies for patients with DTC has been extended into aiding 131I ablation for post-surgical thyroid remnant. Recent studies have revealed the potential of rhTSH in enhancing 131I uptake for metastatic DTC foci and non-toxic multi-nodular goiter （MNG） as well as in strengthening 18F-FDG PET scans for characterizing DTC lesions and helping differential diagnosis of con- genital hypothyroidism. |
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| Keywords: | Thyrotropin Recombinant Thyroid diseases Trends |
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