芪苈强心胶囊治疗慢性心力衰竭34例临床观察

目的观察芪苈强心胶囊治疗慢性心力衰竭(CHF)的临床疗效。方法将68例CHF患者随机分为2组。对照组34例予常规西医治疗,治疗组34例在对照组治疗基础上加芪苈强心胶囊治疗。2组均5个月为1个疗程,治疗1个疗程后观察患者免疫力改善情况、心功能改善情况、6 min步行距离及生活质量评分变化。结果治疗1、5个月后,治疗组免疫力改善率均较对照组高(P<0.05),治疗组改善机体免疫力远期疗效优于对照组。治疗1、3、5个月后,治疗组心功能改善率均较对照组高(P<0.05),远期疗效优于对照组。2组治疗3、5个月后6 min步行距离较本组治疗前提高(P<0.05,P<0.01),且治疗组提高明显(P<0.05,P<0.01)。2组治疗后生活质量评分较本组治疗前均提高(P<0.05,P<0.01),且治疗组提高明显(P<0.05,P<0.01)。结论芪苈强心胶囊治疗CHF,可强心利尿,改善心功能,虽起效慢,但远期效果更好;长期应用可益气温阳,补气固表,增强免疫功能,减少呼吸道发病率,降低再住院率。

Clinical experience of Qiliqiangxin capsule in treatment of patients with chronic congestive heart failure

Objective To study the clinical effect of Qiliqiangxin capsule in treatment of patients with chronic congestive heart failure （CHF）. Methods 68 CHF patients were randomly divided into the treatment group （ n = 34） and the control group （ n = 34） and both groups were all enhanced cardiac contractility and diuretic etc routine therapy of Western medicine but the treatment group treated with Qiliqiangxin capsule. The immunity, the heart function, the six minutes walking experiment and the quality of life score were observed after five - month treatment （ a course）. Re- suits The improvement rate of immunity in treatment group was higher than that in control group after 1, 5 months （ P 〈 O. 05 ）. Long - term effects of improving the immunity in treatment group were superior to that in control group. Improvement rate of cardiac function in treatment group was higher than that in control group after 1, 3 and 5 months （ P 〈 0.05 ）. The six minutes walking distance after treatment group was increased as compared with those before treatment in two groups after 3 and 5 months （P 〈 0.05, P 〈 0.01 ）. The improvement in treatment group was obvi- ous. Conclusion Qiliqiangxin capsule can improve heart function, is cardiac diuretic but the slow onset and better long - term effect ; long - term application can benefit qi to warm yang, benefit qi and consolidating superficies, and enhance immune function, reduce the respiratory morbidity, lower readmission rates.