548例手足口病临床分析

目的:探讨本市手足口病的发病特点、临床表现及流行特征。方法:对我院2008年5月～2010年3月住院的548例手足口病患儿的临床资料进行回顾性分析。结果:2008年发病人数为121人,2009年为361人,2010年1～3月为66人。主要发病人群为1～5岁的儿童(占72.45%),尤其是1～3岁儿童(占50.73%)。男女之比为1.597∶1。所有病例均有皮疹,所有病例中发热患儿233例,占42.52%,心肌损伤者210例,占38.32%。548例病例中普通病例546例,占99.64%,重症病例2例,占0.36%。结论:本市手足口病近年来发病率呈上升趋势,以普通病例为主,多见于1～5岁的幼儿,表现为皮疹及发热,可伴有心肌损伤。只要及时发现、及早治疗,预后良好。

Clinical analysis of hand-foot-mouth disease in 548 cases

Objective：To investigate the pathogenesis,clinical manifestations and epidemiological characteristics of hand-foot-mouth disease（HFMD）.Methods：The clinical data were reviewed in 548 in-patients with HFMD between May 2008 and Mar 2010.Results：The prevalence was 121 in 2008,361 in 2009 and 66 between Jan and Mar in 2010.Most cases occurred in children aged from one to five（72.45%）,especially those aged between one and three（50.73%）,with male to female of 1.597∶1.Skin rash was seen in the total cases.Fever was found in 233（42.52%）and myocardial damage in 210（38.32%）.546 in 548 were simple cases（99.64%）and 2,severe ones（0.36%）.Conclusion：HFMD tends to increase in recent years in our city and is characterized by simple cases,most commonly affecting the children aged from one to five,with symptoms of skin rash,fever and even myocardial injury.The prognosis may be good,given early diagnosis and therapy.