| 树突状细胞在动脉粥样硬化中的作用 |
| |
| 引用本文： | 刘鹏,刘亚杰,陈绍辉.树突状细胞在动脉粥样硬化中的作用[J].国际脑血管病杂志,2011,19(11). |
| |
| 作者姓名： | 刘鹏 刘亚杰 陈绍辉 |
| |
| 作者单位： | 南方医科大学珠江医院神经内科,广州,510282 |
| |
| 摘 要： | 基础和临床研究均证实,炎症反应在动脉粥样硬化(atherosclerosis,AS)的发生、发展及其导致的临床事件过程中起着重要作用.在发生AS的血管内膜和粥样斑块中可见T淋巴细胞、巨噬细胞以及树突状细胞(dendritic cell,DC)聚集现象.作为激活T淋巴细胞最主要的抗原提呈细胞,DC具有决定T淋巴细胞活化、凋亡以及聚集等的重要功能.文章就DC与AS病变的相关性进行了综述.
|
| 关 键 词： | 树突状细胞 炎症 动脉粥样硬化 颈动脉疾病 颅内动脉硬化 |
The role of dendritic cells in atherosclerosis |
| |
| LIU Peng,LIU Ya-jie,CHEN Shao-hui.The role of dendritic cells in atherosclerosis[J].International Journal of Cerebrovascular Diseases,2011,19(11). |
| |
| Authors: | LIU Peng LIU Ya-jie CHEN Shao-hui |
| |
| Abstract: | Both basic and clinical studies have confirmed that inflammatory response plays an important role in the occurrence and development of atherosclerosis (AS) as well as its caused clinical events.The aggregation phenomena of T lymphocytes,macrophages and dendritic cells (DCs) can be observed in intima and atherosclerotic plaques in the event of atherosclerosis.As the most important antigen-presenting cells activating T lymphocytes,DCs have the important functions of determining T lymphocyte activation,apoptosis,and aggregation.This article reviews the correlation between DCs and atherosclerotic lesions. |
| |
| Keywords: | Dendritic cells Inflammation Atherosclerosis Carotid artery diseases Intracranial arteriosclerosis |
| 本文献已被 万方数据 等数据库收录！ |
|
