| 含吲哚美辛宫内节育器中吲哚美辛的作用及其机制 |
| |
| 引用本文： | 修瑞杰,顾向应.含吲哚美辛宫内节育器中吲哚美辛的作用及其机制[J].国际生殖健康/计划生育杂志,2011,30(6):454-457. |
| |
| 作者姓名： | 修瑞杰 顾向应 |
| |
| 作者单位： | 300052 天津医科大学总医院妇产科 |
| |
| 摘 要： | 宫内节育器（IUD）是中国育龄妇女使用最广泛的避孕工具，经量增多、经间点滴出血是IUD的主要不良反应。含吲哚美辛的IUD不仅能发挥良好的避孕效果，而且能避免置器后经量增多、经间点滴出血的不良反应。大量研究表明，吲哚美辛能抑制哺乳动物排卵。因此，研究者对这类含有吲哚美辛IUD的作用机制有了新的认识和探讨空间，即含吲哚美辛的IUD是否有抑制女性排卵、抑制卵子受精的作用。
|
| 关 键 词： | 宫内避孕器 含药 吲哚美辛 避孕 药理作用分子作用机制 月经过多 |
Effect of Indomethacin Contained in the Indomethacin-releasing Intrauterine Device and Its Mechanism |
| |
| XIU Rui-jie,GU Xiang-ying.Effect of Indomethacin Contained in the Indomethacin-releasing Intrauterine Device and Its Mechanism[J].Journla of International Reproductive Health/Family Planning,2011,30(6):454-457. |
| |
| Authors: | XIU Rui-jie GU Xiang-ying |
| |
| Institution: | Ｔｉａｎｊｉｎ Ｍｅｄｉｃａｌ Ｕｎｉｖｅｒｓｉｔｙ General Hospital， Ｔｉａｎjｉｎ ３０００52， Ｃｈｉｎａ |
| |
| Abstract: | Intrauterine device（IUD） is the most widely used contraceptive method in fertile woman in China. The main side effects of IUD are hypermenorrhea and bit bleeding in menstrual interphase. Indomethacin-releasing IUD is a efficient contraceptive， efficaciously preventing those side effects. A lot of study suggested that indomethacin inhibited ovulation in mammals. It is necessary to study the effects of inclomthacin-releasing IUD and its new mechanism to clarify whether indomethacin-releasing IUD inhibit ovulation and fertilization in the human famale. |
| |
| Keywords: | ntrauterine devices medicated Indomethacin Contraception Molecular mechanisms of pharmacological action Menorrhagia |
| 本文献已被 万方数据 等数据库收录！ |
| 点击此处可从《国际生殖健康/计划生育杂志》浏览原始摘要信息 |
| 点击此处可从《国际生殖健康/计划生育杂志》下载免费的PDF全文 |
