双相情感障碍伴自杀行为的流行病学分析

目的分析双相情感障碍伴自杀行为患者的流行病学特征,提高对其诊治水平。方法选取2016年5月至2018年5月洛阳市第五人民医院(太康路院区)精神科收治的186例双相情感障碍患者,年龄(43.15±5.66)岁,年龄范围为23~55岁,对患者流行病学特征进行统计,并通过logistic回归分析与各种危险因素之间的关系。结果根据有无自杀行为将患者分为有自杀行为组(n=96)和无自杀行为组(n=90),两组患者性别、婚姻状况、人际关系、是否为独生子女方面比较,差异无统计学意义(P>0.05);两组患者年龄、吸烟史、精神异常史、饮酒史方面比较,差异有统计学意义(P<0.05)。男性有自杀行为组与男性无自杀行为组患者年龄、婚姻状况、吸烟史、人际关系、是否为独生子方面比较,差异无统计学意义(P>0.05);男性有自杀行为组与男性无自杀行为组患者精神异常史、是否饮酒、家族自杀史、既往自杀史比较,差异有统计学意义(P<0.05)。女性有自杀行为组与女性无自杀行为组患者婚姻状况、人际关系、是否为独生子女方面比较,差异无统计学意义(P>0.05);女性有自杀行为组与女性无自杀行为组患者年龄、吸烟史、精神异常史、饮酒史、家族自杀史、既往自杀史方面比较,差异有统计学意义(P<0.05)。logistic回归分析显示,女性、年龄大、重大精神创伤、既往自杀史与双相情感障碍伴自杀行为均呈正相关。结论女性、年龄大、有重大精神创伤、有自杀家族史、既往自杀史等都可能是双相情感障碍伴自杀行为患者的危险因素临床上应给予高度重视并及早采取干预措施,以免延误最佳治疗时机。

Epidemiological analysis of bipolar disorder with suicidal behavior

Objective To analyze the epidemiological characteristics of patients with bipolar disorder and suicidal behavior,so as to improve the diagnosis and treatment of the disease.Methods A retrospective study was performed on 186 patients with bipolar disorder who were admitted to the department of Psychiatry at the Fifth People′s Hospital of Luoyang from May 2016 to May 2018,aged(43.15±5.66)years old,ranging from 23 to 55 years old.The epidemiological characteristics of the two groups of patients were statistically analyzed,and the relationship between them and various risk factors was analyzed by logistic regression analysis.Results Patients were divided into the suicidal behavior group(n=96)and non-suicidal behavior group(n=90).There were no statistically significant differences between the two groups in terms of gender,marital status,interpersonal relationship,and only-child or not(P>0.05);the differences in age,smoking history,history of mental disorders,and drinking history were statistically significant(P<0.05).There were no significant differences in age,marital status,smoking history,interpersonal relationship,and only-child or not between male patients with and without suicidal behaviors(P>0.05);the differences in history of mental disorders,drinking history,family history of suicide,and previous suicide history were statistically significant(P<0.05).There were no significant differences in marital status,interpersonal relationship,and only-child or not between female patients with and without suicidal behaviors(P>0.05);the differences in age,smoking history,history of mental disorders,drinking history,family history of suicide,and previous suicide history were statistically significant(P<0.05).Logistic regression analysis showed that female,advanced age,major mental trauma,and previous suicide history were positively correlated with bipolar disorder with suicidal behavior.Conclusion Female,advanced age,major mental trauma,family history of suicide,and previous suicide history may be risk factors for bipolar disorder with suicidal behavior.Clinical attention and early intervention should be given to avoid delay in the best treatment.