血糖保护剂-D.L-甘油醛的应用评价

目的 探讨D．L—甘油醛对全血样本中血糖的保护作用。方法 收集志愿者和糖尿病病人的肝素化抗凝全血，加入含或不含D．L—甘油醛的试管中，经过不同时间的孵育后，用生化分析仪测定血浆中的血糖和其它常规生化项目的浓度。结果 加入4．0mmol/L D．L—甘油醛即对血糖具有保护作用，8.0mmol/L D．L—甘油醛在8h内稳定血糖浓度并对其它项目的常规分析没有大的干扰。结论 D．L—甘油醛可有效地保护全血中的血糖浓度在8h内基本稳定，用D.L—甘油醛处理的样本对其它项目的常规分析没有大的干扰。

Evaluation of Effect for D.L- Glyceraldehyde Preserves Blood Glucose Concentration

Objectives To study the effect of D.L-Glyceraldehyde(D.L-GA) on preserve blood glucose concentration.Methods Heparinized blood from volunteers and diabetic patients was added into tubes in which contained or without D.L-GA. After incubation for various times. Plasma glucose and other common clinical biochemical tests were determined with biochemistry analyzers.Results Glucose concentration was effectively preserved in whole blood specimens by 4 0mmol/L D.L-GA. Blood glucose concentration in the specimens treated with 8 0mmol/L D.L-GA were stable and most routine biochemical tests were uninterfered by the presence of D.L-GA.Conclusions D.L-GA effectively preserves glucose concentration in whole blood specimens within 8h. Specimens treated with 8.0mmol/L D.L-GA are suitable for analysis of clinicial routine biochemical tests including determination of blood glucose concentration.