Familial amyotrophic lateral sclerosis,dementia, and psychosis

Reports of amyotrophic lateral sclerosis (ALS) associated with dementia in families outside the Western Pacific have been rare. The authors present a neuropsychiatric survey of three generations of a family with adult-onset ALS with dementia and psychosis in each generation. Among the interesting findings were possible genetic links due to regional inbreeding and a consanguineous marriage