| 胰岛素抵抗与2型糖尿病合并非酒精性脂肪肝关系的研究 |
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| 引用本文： | 阮勇,王静,阮芸,谭擎缨. 胰岛素抵抗与2型糖尿病合并非酒精性脂肪肝关系的研究[J]. 中华糖尿病杂志, 2009, 17(1): 44-45 |
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| 作者姓名： | 阮勇 王静 阮芸 谭擎缨 |
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| 作者单位： | 解放军第117医院内分泌科,杭州,310013 |
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| 摘 要： | 研究胰岛素抵抗与2型糖尿病（T2DM）合并非酒精性脂肪肝（NAFL）的关系，发现T2DM伴有脂肪肝组BMI、WHR、TC、TG、血尿酸、丙氨酸氨基转移酶、γ-谷氨酰转移酶和HOMA-IR较T2DM不伴脂肪肝组升高（P均〈0．01）；Logistic回归分析表明，HOMA—IR、TC、TG、WHR是NAFL形成的独立危险因素。
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| 关 键 词： | 糖尿病 2型 脂肪肝 非酒精性 胰岛素抵抗 |
Analysis of relationship of insulin resistance with T2DM complicated with nonalcoholic fatty liver disease |
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| Affiliation: | RUAN Yong , WANG Jing , RUAN Yuan, et al.( Department of Endocrinology, Chinese PLA 117 Hospital, Hangzhou 310013, China) |
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| Abstract: | The relationship of insulin resistance with nonalcoholic fatty liver disease complicated with type 2 diabetes was studied. The results showed that patients with type 2 diabetes plus nonalcoholic fatty liver（n= 75） had markedly higher levels of body mass index, waist to hip ratio, total cholesterol, triglyceride,hyperuricemia and HOMA-IR than patients with type 2 diabetes without nonalcoholic fatty live （n=54） （P〈 0.01）. Logistic regression analysis showed that HOMA-IR, TC, TG, WHR were the independent risk factors for developing nonalcoholic fatty liver. |
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| Keywords: | Diabetes, type 2 Fatty liver, nonalcoholic Insulin resistance |
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