短暂性脑缺血发作进展为脑梗死危险因素分析

目的:探讨短暂性脑缺血发作(TIA)进展为脑梗死的危险因素。方法:选取129例TIA患者,其中32例在6个月内最终进展为脑梗死(脑梗死组),97例病情未进展(TIA组);对2组临床资料进行对比,并将所得数据进行统计学分析。结果:脑梗死组有高血压史、颈动脉不稳定斑块、糖尿病史、发作持续时间≥30 min和发作次数≥3次,均高于TIA组(P<0.05～P<0.01)。2组患者性别、有无吸烟史和有无冠心病史差异均无统计学意义(P>0.05)。脑梗死组患者年龄大于TIA组(P<0.05)。而2组患者空腹血糖、三酰甘油、胆固醇、低密度脂蛋白和血尿酸水平差异均无统计学意义(P>0.05)。结论:TIA发作持续时间长、发作次数多,尤其有高血压病、糖尿病、高龄、颈动脉不稳定斑块者短期内进展为脑梗死的危险性较高。

Analysis of risk factors associated with cerebral infarction due to transient ischemia attack

Objective: To investigate the risk factors of transient ischemic attack(TIA) evolving into cerebral infarction.Methods: The clinical data of 32 cases with TIA evolving into cerebral infarction(cerebral infarction group) and 97 cases with TIA no-evolving into cerebral infarction(TIA group) within 6 months were statistically analysed.Results: The indicators of hypertension,unstable carotid plaques,diabetes,duration of attack more than or equal to 30 minutes and attack frequency more than or equal to 3 times in cerebral infarction group were higher than those in TIA group(P<0.05 to P<0.01).The differences of sex,smoking history and coronary heart disease between two groups were not statistically significant(P>0.05).The patient age of cerebral infarction group was higher than that in TIA group(P<0.05).The differences of the levels of FBG,triglycerides,cholesterol,LDL and serum uric acid between two groups were not statistically significant(P>0.05).Conclusions: The incidences of TIA evolving into cerebral infarction in the patients with long lasting time and frequent attacking of TIA complicated with hypertension,diabetes,advanced age and unstable carotid plaques are higher.