Diagnosis and non-surgical treatment of bile duct carcinoma: developments in the past decade |
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Authors: | Kiichi Tamada Kentaro Sugano |
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Institution: | (1) Department of Gastroenterology, Jichi Medical School, 3311-1 Yakushiji, Tochigi 329-0498, Japan, JP |
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Abstract: | In the past decade, ultrasonography and magnetic resonance cholangiography have become useful modalities for the screening
of bile duct cancer. Intraductal ultrasonography, using a thin-caliber (2.0 to 2.4 mm in diameter) and high-frequency (15
to 20 MHz) probe, has become a promising modality in assessing locoregional staging. For interventional therapy of unresectable
bile duct carcinoma, metallic stents also became an excellent modality. However, tumor ingrowth and overgrowth into the mesh
of stents are problems to be solved, and external radiation therapy is widely conducted to control the tumor. To improve the
limitations of external radiation, brachytherapy, photodynamic therapy, and microwave coagulation therapy are conducted. However,
these modalities are available in only a limited number of institutions even now. To predict the prognosis of the patients,
approaches using molecular biology must be established.
Received: October 26, 1999 / Accepted: November 26, 1999 |
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Keywords: | : bile duct cancer bile duct carcinoma intraductal ultrasonography metallic stent molecular biology |
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